Evidence map›Paper›PMID 26944281›Full record

ArticleJournal of the American Society for Mass Spectrometry2016

Ion Mobility Separation of Peptide Isotopomers.

Julia L Kaszycki, Andrew P Bowman, Alexandre A Shvartsburg

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  13. Review
  14. Towards the Analysis of High Molecular Weight Proteins and Protein complexes using TIMS-MS.International journal for ion mobility spectrometry : official publication of the International Society for Ion Mobility Spectrometry · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julia L KaszyckiDepartment of Chemistry, Wichita State University, 1845 Fairmount, Wichita, KS, 67260-0051, USA.
Andrew P BowmanDepartment of Chemistry, Wichita State University, 1845 Fairmount, Wichita, KS, 67260-0051, USA.
Alexandre A ShvartsburgDepartment of Chemistry, Wichita State University, 1845 Fairmount, Wichita, KS, 67260-0051, USA. alexandre.shvartsburg@wichita.edu.

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SUSAN J. BROWN · 2012 to 2026
$63.0M
NIGMS NIH HHS P20 GM103418
6 · The paper itself

Abstract

Differential or field asymmetric waveform ion mobility spectrometry (FAIMS) operating at high electric fields fully resolves isotopic isomers for a peptide with labeled residues. The naturally present isotopes, alone and together with targeted labels, also cause spectral shifts that approximately add for multiple heavy atoms. Separation qualitatively depends on the gas composition. These findings may enable novel strategies in proteomic and metabolomic analyses using stable isotope labeling.

Indexed as

Carbon IsotopesIonsIsomerismIsotope LabelingMass SpectrometryNitrogen IsotopesPeptidesCarbon IsotopesIonsNitrogen IsotopesPeptidesDifferential IMS (FAIMS)Ion mobility spectrometryIsotopic analysesIsotopomers

Identifiers

PMID26944281
PMCPMC5030822

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.