Evidence map›Paper›PMID 26943802›Full record

ReviewCellular and molecular life sciences : CMLS2016

Contribution of MicroRNAs to autoimmune diseases.

Lucien P Garo, Gopal Murugaiyan

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 161 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Ocular myasthenia gravis management.Frontiers in neurology · 2025
    Review
  7. Article
  8. Article
  9. Molecular Morbidity Score-Can MicroRNAs Assess the Burden of Disease?International journal of molecular sciences · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Frontiers in genetics · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Lucien P GaroAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, 02115, USA.
Gopal MurugaiyanAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, 02115, USA. mgopal@rics.bwh.harvard.edu.
Brigham and Women's Hospital · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs are a class of evolutionarily conserved, short non-coding RNAs that post-transcriptionally modulate the expression of multiple target genes. They are implicated in almost every biological process, including pathways involved in immune homeostasis, such as immune cell development, central and peripheral tolerance, and T helper cell differentiation. Alterations in miRNA expression and function can lead to major dysfunction of the immune system and mediate susceptibility to autoimmune disease. Here, we discuss the role of miRNAs in the maintenance of immune tolerance to self-antigens and the gain or loss of miRNA functions on tissue inflammation and autoimmunity.

Indexed as

Gene Expression RegulationAnimalsAutoantigensAutoimmune DiseasesAutoimmunityCell DifferentiationDendritic CellsEncephalomyelitis, Autoimmune, ExperimentalHomeostasisHumansImmune SystemImmune ToleranceInflammationMiceMicroRNAsMultiple SclerosisAutoantigensMicroRNAsMIRN146 microRNA, humanMirn146 microRNA, mouseMIRN155 microRNA, humanMirn155 microRNA, mouseMIRN21 microRNA, humanMIRN21 microRNA, mouseDendritic cellsExperimental Autoimmune Encephalomyelitis (EAE)Immune toleranceMicroRNA therapeuticsmiR-146amiR-155miR-21Multiple sclerosis (MS)Th17

Identifiers

PMID26943802
PMCPMC11108434
OpenAlexW2290674316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.