Evidence map›Paper›PMID 26943348›Full record

ArticleJournal of vision2016

Saccadic latency in amblyopia.

Suzanne P McKee, Dennis M Levi, Clifton M Schor, J Anthony Movshon

Open access · goldAbstract read
In one paragraph

Article in Journal of vision, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. First-order basis of second-order temporal loss in amblyopia.Journal of translational medicine · 2026
    Article
  3. Article
  4. Review
  5. Fixation Stability Deficits in Anisometropic Amblyopia.Investigative ophthalmology & visual science · 2025
    Article
  6. Measuring the Interocular Delay and its Link to Visual Acuity in Amblyopia.Investigative ophthalmology & visual science · 2024
    Article
  7. Article
  8. Article
  9. Decomposing the Response Time in Amblyopia: A Drift Diffusion Model Analysis.Investigative ophthalmology & visual science · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Rethinking amblyopia 2020.Vision research · 2020
    Review
  16. Article
  17. Article
  18. Attention deficits in Amblyopia.Current opinion in psychology · 2019
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Suzanne P McKee
Dennis M Levi
Clifton M Schor
J Anthony Movshon
University of California, Berkeley · USNew York University · USSmith-Kettlewell Eye Research Institute · US

Funding

COOPERATIVE AMBLYOPIA CLASSIFICATION STUDYU10EY007657 · NEI · SMITH-KETTLEWELL EYE RESEARCH INSTITUTE · PI MCKEE, SUZANNE P · 1988 to 1995
–
NEI NIH HHS U10 EY07657
6 · The paper itself

Abstract

We measured saccadic latencies in a large sample (total n = 459) of individuals with amblyopia or risk factors for amblyopia, e.g., strabismus or anisometropia, and normal control subjects. We presented an easily visible target randomly to the left or right, 3.5° from fixation. The interocular difference in saccadic latency is highly correlated with the interocular difference in LogMAR (Snellen) acuity-as the acuity difference increases, so does the latency difference. Strabismic and strabismic-anisometropic amblyopes have, on average, a larger difference between their eyes in LogMAR acuity than anisometropic amblyopes and thus their interocular latency difference is, on average, significantly larger than anisometropic amblyopes. Despite its relation to LogMAR acuity, the longer latency in strabismic amblyopes cannot be attributed either to poor resolution or to reduced contrast sensitivity, because their interocular differences in grating acuity and in contrast sensitivity are roughly the same as for anisometropic amblyopes. The correlation between LogMAR acuity and saccadic latency arises because of the confluence of two separable effects in the strabismic amblyopic eye-poor letter recognition impairs LogMAR acuity while an intrinsic sluggishness delays reaction time. We speculate that the frequent microsaccades and the accompanying attentional shifts, made while strabismic amblyopes struggle to maintain fixation with their amblyopic eyes, result in all types of reactions being irreducibly delayed.

Indexed as

AdolescentAdultAmblyopiaAnisometropiaChildContrast SensitivityFemaleHumansMaleReaction TimeSaccadesStrabismusVisual AcuityYoung Adult

Identifiers

PMID26943348
PMCPMC5089444
OpenAlexW2292600668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.