Evidence map›Paper›PMID 26943113›Full record

Trial reportThe American journal of occupational therapy : official publication of the American Occupational Therapy Association

Combined Cognitive-Strategy and Task-Specific Training Affects Cognition and Upper-Extremity Function in Subacute Stroke: An Exploratory Randomized Controlled Trial.

Timothy J Wolf, Helene Polatajko, Carolyn Baum, Jorge Rios, Dianne Cirone, Meghan Doherty, Sara McEwen

3 registry-linked trialsOpen access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The American journal of occupational therapy : official publication of the American Occupational Therapy Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01309165 nacompletednot on this map

Exploring the Efficacy of Combined Task-Specific and Cognitive Strategy Training in Subacute Stroke: A Phase II Clinical Trial.

TypeinterventionalSponsorSt. John's Rehab HospitalRan2011 to 2013Enrolled35ConditionsStrokeArmsCO-OP, Standard Occupational Therapy
NCT05248178 naterminatednot on this map

Pilot Testing of tDCS and Metacognitive Strategy Training in Chronic Stroke

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2022 to 2025Enrolled11ConditionsChronic StrokeArmsCO-OP Procedures, tDCS, Computer Cognitive Training Procedures, sham tDCS group
NCT06136871 nacompletednot on this map

Cognitive Strategy Training in Post-COVID-19 Syndrome: A Feasibility Trial

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2024 to 2025Enrolled65ConditionsPost-COVID-19 SyndromeArmsCO-OP Procedures, Inactive Control Group
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Occupational therapy for cognitive impairment in stroke patients.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Pooled it
  3. Trial
  4. Lesion location may attenuate response to strategy training in acute stroke.PM & R : the journal of injury, function, and rehabilitation · 2022
    Trial
  5. Trial
  6. Review
  7. Article
  8. Comparing the CO-OP ApproachBrain sciences · 2025
    Article
  9. Remotely Delivered Task-Oriented Training and Evaluation (reTOTE) for Stroke Rehabilitation.Archives of rehabilitation research and clinical translation · 2025
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Reversing the Ruin: Rehabilitation, Recovery, and Restoration After Stroke.Current neurology and neuroscience reports · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Timothy J WolfTimothy J. Wolf, OTD, MSCI, OTR/L, FAOTA, is Associate Professor and Chair, Department of Occupational Therapy, University of Missouri, Columbia; wolftj@health.missouri.edu.
Helene PolatajkoHelene Polatajko, PhD, OT Reg. (Ont.), is Professor, Rehabilitation Sciences Institute and Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Ontario, Canada.
Carolyn BaumCarolyn Baum, PhD, OTR/L, FAOTA, is Professor and Chair, Program in Occupational Therapy, and Professor, Department of Neurology, Washington University School of Medicine, St. Louis, MO.
Jorge RiosJorge Rios, BSc, is Lab Manager, St. John's Rehab Research Program, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Dianne CironeDianne Cirone, MSc(RS), OT Reg. (Ont.), is Lecturer, Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Ontario, Canada, and Occupational Therapist, St. John's Rehab Outpatient Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Meghan DohertyMeghan Doherty, MSOT, OTR/L, is Clinical Specialist, Program in Occupational Therapy, Washington University School of Medicine, St. Louis, MO.
Sara McEwenSara McEwen, PhD, is Assistant Professor, Rehabilitation Sciences Institute and Department of Physical Therapy, University of Toronto, Toronto, Ontario, Canada, and Scientist, St. John's Rehab Research Program, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Washington University in St. Louis · USHealth Sciences Centre · CASunnybrook Health Science Centre · CAToronto Rehabilitation Institute · CAUniversity of Missouri Health System · USUniversity of Toronto · CA

Funding

MULTICENTER CAREER DEVELOPMENT PROGRAM FOR PHYSICAL AND OCCUPATIONAL THERAPYK12HD055931 · NICHD · WASHINGTON UNIVERSITY · PI HAYES, MARCIE HARRIS · 2007 to 2021
$12.7M
CLINICAL EFFECTIVENESS OF SELF MANAGEMENT INTERVENTION POST-MILD STROKEK23HD073190 · NICHD · WASHINGTON UNIVERSITY · PI WOLF, TIMOTHY J. · 2012 to 2015
$389k
Canadian Institutes of Health Research 111200NICHD NIH HHS K12 HD055931NICHD NIH HHS K12HD055931NICHD NIH HHS K23 HD073190NICHD NIH HHS K23HD073190
6 · The paper itself

Abstract

The purpose of this study was to estimate the effect of Cognitive Orientation to Daily Occupational Performance (CO-OP) compared with usual occupational therapy on upper-extremity movement, cognitive flexibility, and stroke impact in people less than 3 mo after stroke. An exploratory, single-blind randomized controlled trial was conducted with people referred to outpatient occupational therapy services at two rehabilitation centers. Arm movement was measured with the Action Research Arm Test, cognitive flexibility with the Delis-Kaplan Executive Function System Trail Making subtest, and stroke impact with subscales of the Stroke Impact Scale. A total of 35 participants were randomized, and 26 completed the intervention. CO-OP demonstrated measurable effects over usual care on all measures. These data provide early support for the use of CO-OP to improve performance and remediate cognitive and arm movement impairments after stroke over usual care; however, future study is warranted to confirm the effects observed in this trial.

Indexed as

CognitionStroke RehabilitationUpper ExtremityActivities of Daily LivingHumansNeurological RehabilitationOccupational TherapyRecovery of FunctionSingle-Blind MethodTask Performance and Analysis

Identifiers

PMID26943113
PMCPMC4776734
OpenAlexW2291571240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.