Evidence map›Paper›PMID 26942768›Full record

SynthesisEating and weight disorders : EWD2016

A systematic review of the health-related quality of life and economic burdens of anorexia nervosa, bulimia nervosa, and binge eating disorder.

Tamás Ágh, Gábor Kovács, Dylan Supina, Manjiri Pawaskar, Barry K Herman, Zoltán Vokó, David V Sheehan

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Eating and weight disorders : EWD, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06063278 (Step by Step Group Therapy for Bulimia Nervosa), which is not on this map. Cited by 187 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06063278 nacompletednot on this mapstarted 2022, after this paper: background citation

Step by Step Group Therapy for Bulimia Nervosa: Effectiveness and Mechanisms of Change.

TypeinterventionalSponsorFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauRan2022 to 2024Enrolled100ConditionsBulimia NervosaArmsl Group Therapy for BN.
3 · Its place in the literature

Who cites it

187 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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  8. A systematic review on the role of microbiota in the pathogenesis and treatment of eating disorders.European psychiatry : the journal of the Association of European Psychiatrists · 2020
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127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tamás ÁghSyreon Research Institute, 119 Thököly Street, 1146, Budapest, Hungary. tamas.agh@syreon.eu.
Gábor KovácsSyreon Research Institute, 119 Thököly Street, 1146, Budapest, Hungary.
Dylan SupinaFormerly of Shire, 300 Shire Way, Lexington, MA, 02421, USA.
Manjiri PawaskarFormerly of Shire, 300 Shire Way, Lexington, MA, 02421, USA.
Barry K HermanShire, 300 Shire Way, Lexington, MA, 02421, USA.
Zoltán VokóSyreon Research Institute, 119 Thököly Street, 1146, Budapest, Hungary.
David V SheehanUniversity of South Florida College of Medicine, 12901 Bruce B. Downs Boulevard, Tampa, FL, 33612, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo perform a systematic review of the health-related quality of life (HRQoL) and economic burdens of anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED).

methodsA systematic literature search of English-language studies was performed in Medline, Embase, PsycINFO, PsycARTICLES, Academic Search Complete, CINAHL Plus, Business Source Premier, and Cochrane Library. Cost data were converted to 2014 Euro.

resultsSixty-nine studies were included. Data on HRQoL were reported in 41 studies (18 for AN, 17 for BN, and 18 for BED), on healthcare utilization in 20 studies (14 for AN, 12 for BN, and 8 for BED), and on healthcare costs in 17 studies (9 for AN, 11 for BN, and only 2 for BED). Patients' HRQoL was significantly worse with AN, BN, and BED compared with healthy populations. AN, BN, and BED were associated with a high rate of hospitalization, outpatient care, and emergency department visits. However, patients rarely received specific treatment for their eating disorder. The annual healthcare costs for AN, BN, and BED were €2993 to €55,270, €888 to €18,823, and €1762 to €2902, respectively.

conclusionsAN, BN, and BED have a serious impact on patient's HRQoL and are also associated with increased healthcare utilization and healthcare costs. The burden of BED should be examined separately from that of BN. The limited evidence suggests that further research is warranted to better understand the differences in long-term HRQoL and economic burdens of AN, BN, and BED.

Indexed as

Cost of IllnessAnorexia NervosaBinge-Eating DisorderBulimia NervosaHealth StatusHumansQuality of LifeAnorexia nervosaBinge eating disorderBulimia nervosaCost of illnessEating disordersQuality of life

Identifiers

PMID26942768
PMCPMC5010619

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.