Evidence map›Paper›PMID 26942743›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2016

Peritonsillar abscess (PTA): clinical characteristics, microbiology, drug exposures and outcomes of a large multicenter cohort survey of 412 patients hospitalized in 13 French university hospitals.

D Lepelletier, V Pinaud, P Le Conte, C Bourigault, N Asseray, F Ballereau, J Caillon, C Ferron, C Righini, E Batard and 2 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 33 citations in OpenAlex.

  1. Association between clinical outcome and microbiological findings in peritonsillar abscess - an observational study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Observational
  2. Diseases associated with subsequent peritonsillar abscess: a case-control-study from ENT practices in Germany.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  3. Unveiling the etiology of peritonsillar abscess using next generation sequencing.Annals of clinical microbiology and antimicrobials · 2023
    Article
  4. Article
  5. Article
  6. Parapharyngeal Abscesses Caused by Group G Streptococcus.Case reports in otolaryngology · 2018
    Article
  7. Review
  8. Is there an association between prior anti-inflammatory drug exposure and occurrence of peritonsillar abscess (PTA)? A national multicenter prospective observational case-control study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Observational
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

D LepelletierBacteriology and Infection Control Department, Nantes University Hospital, 44093, Nantes, France. didier.lepelletier@chu-nantes.fr.
V PinaudEmergency Department, Nantes University Hospital, 44093, Nantes, France.
P Le ConteEmergency Department, Nantes University Hospital, 44093, Nantes, France.
C BourigaultBacteriology and Infection Control Department, Nantes University Hospital, 44093, Nantes, France.
N AsserayInfectious Diseases Department, Nantes University Hospital, 44093, Nantes, France.
F BallereauMedqual, Nantes University Hospital, 44093, Nantes, France.
J CaillonBacteriology and Infection Control Department, Nantes University Hospital, 44093, Nantes, France.
C FerronOtorhinolaryngology Department, Nantes University Hospital, 44093, Nantes, France.
C RighiniOtorhinolaryngology Department, Michallon University Hospital, 38000, Grenoble, France.
E BatardEmergency Department, Nantes University Hospital, 44093, Nantes, France.
G PotelEmergency Department, Nantes University Hospital, 44093, Nantes, France.
French PTA Study Group
Nantes Université · FRHôpital Albert Michallon · FRCentre Hospitalier Universitaire de Nantes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to describe the epidemiology of hospitalized patients with peritonsillar abscess (PTA). We conducted a multicenter survey in 13 French university hospitals in 2009-2012 describing 412 patients. Median age was 29 year (range, 2-84) and current smoking habit was reported by 177 (43 %) patients. Most of the patients (92 %) had consulted a physician for sore throat within 10 days before admission for PTA diagnosis. Additional symptoms such as visible tonsil abnormalities (83 %), tender cervical adenopathy (57 %) and fever ≥ 38.5 °C (53 %) were also reported. A total of 65 % patients (269/412) reported recent systemic anti-inflammatory agents (AIAs) exposure by medical prescription (70 %), self-medication (22 %), or both (8 %); 61 % and 27 % reported recent exposure to antibiotic and topical treatments for sore throat, respectively. Non-steroidal AIAs were used most often (45 %), particularly arylpropionic derivatives. A rapid diagnosis antigen test (RDT) for Streptococcus pyogenes was performed in 70 (17 %) patients and was positive in 17 (24 %), of whom 9 (53 %) were exposed to AIAs and 14 (82 %) to antibiotics. To treat PTA, antibiotic therapy was given to 392 (95 %) patients. Of 333 antibiotic prescriptions, amoxicillin-clavulanic acid and metronidazole were the most prescribed antibiotics (42 and 17 %, respectively). Surgical drainage of the abscess was performed in 119 (29 %) cases and tonsillectomy in 75 (18 %) cases. The clinical outcome was favorable during the hospital stay in 404 (98 %) patients. In conclusion, patients with sore throat are often exposed to AIAs before PTA diagnosis, and antibiotic prescription was not often based on the RDT positivity.

Indexed as

AdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsChildChild, PreschoolComorbidityFemaleFranceHospitalizationHospitals, UniversityHumansMaleMiddle AgedPeritonsillar AbscessAnti-Bacterial Agents

Identifiers

PMID26942743
OpenAlexW2291715248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.