Evidence map›Paper›PMID 26942186›Full record

ReviewFrontiers in veterinary science2016

Impacts of Cereal Ergot in Food Animal Production.

Stephanie Coufal-Majewski, Kim Stanford, Tim McAllister, Barry Blakley, John McKinnon, Alexandre Vieira Chaves, Yuxi Wang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in veterinary science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 85 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Stephanie Coufal-MajewskiFaculty of Veterinary Science, School of Life and Environmental Sciences, University of Sydney, Sydney, NSW, Australia; Lethbridge Research and Development Centre, Agriculture and Agri-Food Canada, Lethbridge, AB, Canada.
Kim StanfordAgriculture Centre, Alberta Agriculture and Forestry , Lethbridge, AB , Canada.
Tim McAllisterLethbridge Research and Development Centre, Agriculture and Agri-Food Canada , Lethbridge, AB , Canada.
Barry BlakleyDepartment of Veterinary Biomedical Sciences, University of Saskatchewan , Saskatchewan, SK , Canada.
John McKinnonDepartment of Animal and Poultry Science, University of Saskatchewan , Saskatchewan, SK , Canada.
Alexandre Vieira ChavesFaculty of Veterinary Science, School of Life and Environmental Sciences, University of Sydney , Sydney, NSW , Australia.
Yuxi WangLethbridge Research and Development Centre, Agriculture and Agri-Food Canada , Lethbridge, AB , Canada.
Agriculture and Agri-Food Canada · CAUniversity of Saskatchewan · CAUniversity of Sydney · AUAgriculture Food and Rural Development · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The negative impacts of ergot contamination of grain on the health of humans and animals were first documented during the fifth century AD. Although ergotism is now rare in humans, cleaning contaminated grain concentrates ergot bodies in screenings which are used as livestock feed. Ergot is found worldwide, with even low concentrations of alkaloids in the diet (<100 ppb total), reducing the growth efficiency of livestock. Extended periods of increased moisture and cold during flowering promote the development of ergot in cereal crops. Furthermore, the unpredictability of climate change may have detrimental impacts to important cereal crops, such as wheat, barley, and rye, favoring ergot production. Allowable limits for ergot in livestock feed are confusing as they may be determined by proportions of ergot bodies or by total levels of alkaloids, measurements that may differ widely in their estimation of toxicity. The proportion of individual alkaloids, including ergotamine, ergocristine, ergosine, ergocornine, and ergocryptine is extremely variable within ergot bodies and the relative toxicity of these alkaloids has yet to be determined. This raises concerns that current recommendations on safe levels of ergot in feeds may be unreliable. Furthermore, the total ergot alkaloid content is greatly dependent on the geographic region, harvest year, cereal species, variety, and genotype. Considerable animal-to-animal variation in the ability of the liver to detoxify ergot alkaloids also exists and the impacts of factors, such as pelleting of feeds or use of binders to reduce bioavailability of alkaloids require study. Accordingly, unknowns greatly outnumber the knowns for cereal ergot and further study to help better define allowable limits for livestock would be welcome.

Indexed as

animal performanceClaviceps purpureaergot alkaloidssclerotiatoxicoses

Identifiers

PMID26942186
PMCPMC4766294
OpenAlexW2310793697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.