ArticleJournal of International Society of Preventive & Community Dentistry2015
Comparing the efficacy of xylitol-containing and conventional chewing gums in reducing salivary counts of Streptococcus mutans: An in vivo study.
Article in Journal of International Society of Preventive & Community Dentistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- A chewing gum containing ethylenediaminetetraaceticacid (EDTA), methyl sulfonyl methane (MSM) and xylitol works comparable to chlorehexidine mouthrinse.Scientific reports · 2024Trial
- Improving Oral Health and Modulating the Oral Microbiome to Reduce Bloodstream Infections from Oral Organisms in Pediatric and Young Adult Hematopoietic Stem Cell Transplantation Recipients: A Randomized Controlled Trial.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020Trial
- The Efficacy of a Chewing Gum Containing Phyllanthus emblica Fruit Extract in Improving Oral Health.Current microbiology · 2018Trial
- Effect of Xylitol and Maltitol Chewing Gums on Plaque Reduction and Salivary pH Modulation: A Retrospective Study in Pediatric Patients.Dentistry journal · 2025Article
- Updates on Caries Risk Assessment-A Literature Review.Dentistry journal · 2024Review
- Enzymatic Synthesis of Maltitol and Its Inhibitory Effect on the Growth ofBiomolecules · 2022Article
- Maltitol: Analytical Determination Methods, Applications in the Food Industry, Metabolism and Health Impacts.International journal of environmental research and public health · 2020Review
- Comparative evaluation of Stevia and Xylitol chewing gum on salivary Streptococcus mutans count - A pilot study.Journal of clinical and experimental dentistry · 2020Article
- The Impact of Maltitol-Sweetened Chewing Gum on the Dental Plaque Biofilm Microbiota Composition.Frontiers in microbiology · 2018Article
- Antibacterial Effects of Different Concentrations ofJournal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveDental caries is among the most common chronic diseases in humans. Streptococcus mutans is generally responsible for most cases of dental caries. The present study sought to compare the effects of xylitol-containing and conventional chewing gums on salivary levels of S. mutans. MATERIALS AND
methodsThis study adopted a crossover design. Two type of chewing gums (one containing 70% xylitol and approved by the Iranian Dental Association, and another containing sucrose) were purchased. The participants were 32 individuals aged 18-35 years whose oral hygiene was categorized as moderate or poor based on a caries risk assessment table. Salivary levels of S. mutans were measured at baseline, after the first and second phases of chewing gums, and after the washout period. The measurements were performed on blood agar and mitis salivarius-bacitracin agar (MSBA). Pairwise comparisons were then used to analyze the collected data.
resultsSalivary levels of S. mutans in both groups were significantly higher during the two stages of chewing gum than in the washout period or baseline. Moreover, comparisons between the two types of gums suggested that chewing xylitol-containing gums led to greater reductions in S. mutans counts. This effect was more apparent in subjects with poor oral hygiene than in those with moderate oral hygiene.
conclusionsXylitol-containing chewing gums are more effective than conventional gums in reducing salivary levels of S. mutans in individuals with poor-moderate oral hygiene.
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