Evidence map›Paper›PMID 26942056›Full record

ArticleOncoimmunology

Failure recovery of circulating NKG2D

Jian Gao, Zhaojun Duan, Ling Zhang, Xiangbo Huang, Lu Long, Jing Tu, Hua Liang, Yu Zhang, Tao Shen, Fengmin Lu

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Dysfunctional Natural Killer Cells in the Aftermath of Cancer Surgery.International journal of molecular sciences · 2017
    Review
  13. Changes in immune profile affect disease progression in hepatocellular carcinoma.International journal of immunopathology and pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Jian GaoState Key Laboratory of Natural and Biomimetic Drugs; The Department of Microbiology & Infectious Disease Center; School of Basic Medicine; Peking University Health Science Center; Beijing, China; These authors made equal contributions to this manuscript.
Zhaojun DuanState Key Laboratory of Natural and Biomimetic Drugs; The Department of Microbiology & Infectious Disease Center; School of Basic Medicine; Peking University Health Science Center; Beijing, China; These authors made equal contributions to this manuscript.
Ling ZhangDepartment of Hepatobiliary and Pancreatic Surgery; Affiliated Tumor Hospital of Zhengzhou University ; Zhengzhou, China.
Xiangbo HuangState Key Laboratory of Natural and Biomimetic Drugs; The Department of Microbiology & Infectious Disease Center; School of Basic Medicine; Peking University Health Science Center ; Beijing, China.
Lu LongState Key Laboratory of Natural and Biomimetic Drugs; The Department of Microbiology & Infectious Disease Center; School of Basic Medicine; Peking University Health Science Center ; Beijing, China.
Jing TuState Key Laboratory of Natural and Biomimetic Drugs; The Department of Microbiology & Infectious Disease Center; School of Basic Medicine; Peking University Health Science Center ; Beijing, China.
Hua LiangState Key Laboratory for Infectious Disease Prevention and Control; National Center for AIDS/STD Control and Prevention; Chinese Center for Disease Control and Prevention; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases ; Beijing, China.
Yu ZhangDepartment of Immunology; Peking University Health Science Center ; Beijing, China.
Tao ShenState Key Laboratory of Natural and Biomimetic Drugs; The Department of Microbiology & Infectious Disease Center; School of Basic Medicine; Peking University Health Science Center ; Beijing, China.
Fengmin LuState Key Laboratory of Natural and Biomimetic Drugs; The Department of Microbiology & Infectious Disease Center; School of Basic Medicine; Peking University Health Science Center ; Beijing, China.
State Key Laboratory of Natural and Biomimetic DrugsPeking University · CNFood and Drug Administration · THNational Center for AIDS/STD Control and Prevention,China CDC · CNTumor Hospital of Guangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysfunction of natural killer (NK) cells has been implicated in the failure of antitumor immune responses in hepatocellular carcinoma (HCC) patients. However, the changes of NK profile in peripheral blood after surgery and tumor tissues of HCC patients, as well as the underlying reason and the significance are vague. Here, we observed that the frequencies of circulating NKG2D

Indexed as

HCCNK cellsNKG2DsMICATGF-β

Identifiers

PMID26942056
PMCPMC4760296
OpenAlexW1828491627

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.