Evidence map›Paper›PMID 26941885›Full record

ArticleThe annals of applied statistics2015

Bayesian Analysis of Ambulatory Blood Pressure Dynamics with Application to Irregularly Spaced Sparse Data.

Zhao-Hua Lu, Sy-Miin Chow, Andrew Sherwood, Hongtu Zhu

Abstract read
In one paragraph

Article in The annals of applied statistics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhao-Hua LuDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Sy-Miin ChowDept. of Human Development and Family Studies, Penn State University, 118 Henderson South Building, University Park, PA 16803.
Andrew SherwoodPsychology and Neuroscience, Duke Universityz, 4569 Hosp South, Campus Box 3119 Med Ctr.
Hongtu ZhuDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
Statistical Analysis of Biomedical Imaging Data in Curved SpaceR01MH086633 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI IBRAHIM, JOSEPH G · 2010 to 2018
$2.9M
Modeling the Dynamics of Early Communication and DevelopmentR01GM105004 · NIGMS · UNIVERSITY OF MIAMI CORAL GABLES · PI CHOW, SY-MIIN, COHN, JEFFREY F · 2013 to 2016
$2.1M
SCH: Proactive Health Monitoring Using Individualized Analysis of Tissue ElasticityR01EB020426 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIN, MING C. · 2014 to 2016
$653k
North Carolina Translational & Clinical Sciences Institute (NC TraCS)TL1TR001110 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$489k
NCATS NIH HHS TL1 TR001110NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1 TR002489NIBIB NIH HHS R01 EB020426NIGMS NIH HHS R01 GM105004NIMH NIH HHS R01 MH086633
6 · The paper itself

Abstract

Ambulatory cardiovascular (CV) measurements provide valuable insights into individuals' health conditions in "real-life," everyday settings. Current methods of modeling ambulatory CV data do not consider the dynamic characteristics of the full data set and their relationships with covariates such as caffeine use and stress. We propose a stochastic differential equation (SDE) in the form of a dual nonlinear Ornstein-Uhlenbeck (OU) model with person-specific covariates to capture the morning surge and nighttime dipping dynamics of ambulatory CV data. To circumvent the data analytic constraint that empirical measurements are typically collected at irregular and much larger time intervals than those evaluated in simulation studies of SDEs, we adopt a Bayesian approach with a regularized Brownian Bridge sampler (RBBS) and an efficient multiresolution (MR) algorithm to fit the proposed SDE. The MR algorithm can produce more efficient MCMC samples that is crucial for valid parameter estimation and inference. Using this model and algorithm to data from the Duke Behavioral Investigation of Hypertension Study, results indicate that age, caffeine intake, gender and race have effects on distinct dynamic characteristics of the participants' CV trajectories.

Indexed as

Irregularly spaced longitudinal dataLatent processMarkov chain Monte CarloMultiresolution algorithmNonlinear processPopulation estimation

Identifiers

PMID26941885
PMCPMC4773035

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.