Evidence map›Paper›PMID 26941735›Full record

ReviewFrontiers in microbiology2016

Surface Proteoglycans as Mediators in Bacterial Pathogens Infections.

Beatriz García, Jesús Merayo-Lloves, Carla Martin, Ignacio Alcalde, Luis M Quirós, Fernando Vazquez

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Pathogens that infect mammalian cells via sulfonated glycosaminoglycans.Frontiers in cellular and infection microbiology · 2025
    Review
  5. Synthesis ofMolecules (Basel, Switzerland) · 2024
    Article
  6. Review
  7. Review
  8. Biomimetic strategies for the deputization of proteoglycan functions.Frontiers in cell and developmental biology · 2024
    Review
  9. Article
  10. Article
  11. Crystal Structures ofJournal of applied glycoscience · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. The Heparanase Regulatory Network in Health and Disease.International journal of molecular sciences · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Glycosaminoglycan-Protein Interactions: The First Draft of the Glycosaminoglycan Interactome.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Beatriz GarcíaDepartment of Functional Biology, Microbiology, Faculty of Medicine, University of OviedoOviedo, Spain; Instituto Oftalmológico Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de OviedoOviedo, Spain.
Jesús Merayo-LlovesInstituto Oftalmológico Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de OviedoOviedo, Spain; Department of Surgery, University of OviedoOviedo, Spain.
Carla MartinDepartment of Functional Biology, Microbiology, Faculty of Medicine, University of OviedoOviedo, Spain; Instituto Oftalmológico Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de OviedoOviedo, Spain.
Ignacio AlcaldeInstituto Oftalmológico Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de Oviedo Oviedo, Spain.
Luis M QuirósDepartment of Functional Biology, Microbiology, Faculty of Medicine, University of OviedoOviedo, Spain; Instituto Oftalmológico Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de OviedoOviedo, Spain.
Fernando VazquezDepartment of Functional Biology, Microbiology, Faculty of Medicine, University of OviedoOviedo, Spain; Instituto Oftalmológico Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de OviedoOviedo, Spain; Service of Microbiology, Central University Hospital of AsturiasOviedo, Spain.
Fernández-Vega Ophthalmological Institute · ESUniversidad de Oviedo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious diseases remain an important global health problem. The interaction of a wide range of pathogen bacteria with host cells from many different tissues is frequently mediated by proteoglycans. These compounds are ubiquitous complex molecules which are not only involved in adherence and colonization, but can also participate in other steps of pathogenesis. To overcome the problem of microbial resistance to antibiotics new therapeutic agents could be developed based on the characteristics of the interaction of pathogens with proteoglycans.

Indexed as

bacteriaglycosaminoglycanshost interactioninfectionproteoglycans

Identifiers

PMID26941735
PMCPMC4764700
OpenAlexW2299755521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.