ArticleFrontiers in behavioral neuroscience2016
Resting-State Coupling between Core Regions within the Central-Executive and Salience Networks Contributes to Working Memory Performance.
Article in Frontiers in behavioral neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Impact of exercise on older adults' mood is moderated by sleep and mediated by altered brain connectivity.Social cognitive and affective neuroscience · 2020Trial
- Closed-loop transcranial alternating current stimulation (tACS) reduces cue reactivity and improves inhibitory control in methamphetamine use disorder with frequency and timing specificity.Molecular psychiatry · 2026Article
- Specific learning disorders and underlying processes: can WISC-IV subtests predict SLD neurocognitive profiles in Italian children aged 7-14 years?Frontiers in psychology · 2026Article
- Examining Smartphone-assessed Executive Function Metrics and Intrinsic Resting-State Functional Connectivity in Depression.Research square · 2025Article
- The association between fronto-insular interaction and executive function during childhood and adolescence in a resting state fMRI study.Scientific reports · 2025Article
- Hypoxia's Impact on Hippocampal Functional Connectivity: Insights from Resting-State fMRI Studies.Brain sciences · 2025Review
- Neural mechanisms of cognitive conflict: processing COVID-19 vaccine misinformation.Frontiers in neuroscience · 2025Article
- Beyond NMDA Receptors: A Narrative Review of Ketamine's Rapid and Multifaceted Mechanisms in Depression Treatment.International journal of molecular sciences · 2024Review
- Functional connectivity is linked to working memory differences in children with reading learning disability.BMC pediatrics · 2024Article
- Wearing a KN95/FFP2 facemask induces subtle yet significant brain functional connectivity modifications restricted to the salience network.European radiology experimental · 2022Article
- Capacity differences in working memory based on resting state brain networks.Scientific reports · 2021Article
- A Review of Working Memory Training in the Management of Attention Deficit Hyperactivity Disorder.Frontiers in behavioral neuroscience · 2021Review
- The Oscillatory Basis of Working Memory Function and Dysfunction in Epilepsy.Frontiers in human neuroscience · 2020Review
- Anterior cingulate GABA and glutamate concentrations are associated with resting-state network connectivity.Scientific reports · 2019Article
- Resting-state connectivity alterations during transient global amnesia.NeuroImage. Clinical · 2019Article
- Mild Cognitive Impairment and Decline in Resting State Functional Connectivity after Total Knee Arthroplasty with General Anesthesia.Journal of Alzheimer's disease : JAD · 2019Article
- Exploring the Neuroplastic Effects of Biofeedback Training on Smokers.Behavioural neurology · 2018Article
- Moderating Effects of Harm Avoidance on Resting-State Functional Connectivity of the Anterior Insula.Frontiers in human neuroscience · 2018Article
- Real World Problem-Solving.Frontiers in human neuroscience · 2018Article
- The Role of Working Memory for Cognitive Control in Anorexia Nervosa versus Substance Use Disorder.Frontiers in psychology · 2017Review
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8 authors.
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Abstract
Previous studies investigated the distinct roles played by different cognitive regions and suggested that the patterns of connectivity of these regions are associated with working memory (WM). However, the specific causal mechanism through which the neuronal circuits that involve these brain regions contribute to WM is still unclear. Here, in a large sample of healthy young adults, we first identified the core WM regions by linking WM accuracy to resting-state functional connectivity with the bilateral dorsolateral prefrontal cortex (dLPFC; a principal region in the central-executive network, CEN). Then a spectral dynamic causal modeling (spDCM) analysis was performed to quantify the effective connectivity between these regions. Finally, the effective connectivity was correlated with WM accuracy to characterize the relationship between these connections and WM performance. We found that the functional connections between the bilateral dLPFC and the dorsal anterior cingulate cortex (dACC) and between the right dLPFC and the left orbital fronto-insular cortex (FIC) were correlated with WM accuracy. Furthermore, the effective connectivity from the dACC to the bilateral dLPFC and from the right dLPFC to the left FIC could predict individual differences in WM. Because the dACC and FIC are core regions of the salience network (SN), we inferred that the inter- and causal-connectivity between core regions within the CEN and SN is functionally relevant for WM performance. In summary, the current study identified the dLPFC-related resting-state effective connectivity underlying WM and suggests that individual differences in cognitive ability could be characterized by resting-state effective connectivity.
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