Evidence map›Paper›PMID 26941579›Full record

ArticleInternational journal of medical sciences2016

A Prospective Randomized Experimental Study to Investigate the Eradication Rate of Endometriosis after Surgical Resection versus Aerosol Plasma Coagulation in a Rat Model.

Ralf Rothmund, Marcus Scharpf, Christos Tsaousidis, Constanze Planck, Markus Dominik Enderle, Alexander Neugebauer, Kristin Kroeker, Daniela Nuessle, Falko Fend, Sara Brucker and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Ralf Rothmund1. Department of Obstetrics and Gynaecology, University of Tuebingen, Calwerstr. 7, 72076 Tuebingen, Germany (Director: Prof. D. Wallwiener);
Marcus Scharpf2. Department of Pathology, University of Tuebingen, Liebermeisterstr. 8, 72076 Tuebingen, Germany (Director: Prof. F. Fend);
Christos Tsaousidis1. Department of Obstetrics and Gynaecology, University of Tuebingen, Calwerstr. 7, 72076 Tuebingen, Germany (Director: Prof. D. Wallwiener);
Constanze Planck1. Department of Obstetrics and Gynaecology, University of Tuebingen, Calwerstr. 7, 72076 Tuebingen, Germany (Director: Prof. D. Wallwiener);
Markus Dominik Enderle3. Erbe Elektromedizin GmbH, Waldhoernlestr. 17, 72072 Tuebingen, Germany.
Alexander Neugebauer3. Erbe Elektromedizin GmbH, Waldhoernlestr. 17, 72072 Tuebingen, Germany.
Kristin Kroeker3. Erbe Elektromedizin GmbH, Waldhoernlestr. 17, 72072 Tuebingen, Germany.
Daniela Nuessle3. Erbe Elektromedizin GmbH, Waldhoernlestr. 17, 72072 Tuebingen, Germany.
Falko Fend2. Department of Pathology, University of Tuebingen, Liebermeisterstr. 8, 72076 Tuebingen, Germany (Director: Prof. F. Fend);
Sara Brucker1. Department of Obstetrics and Gynaecology, University of Tuebingen, Calwerstr. 7, 72076 Tuebingen, Germany (Director: Prof. D. Wallwiener);
Bernhard Kraemer1. Department of Obstetrics and Gynaecology, University of Tuebingen, Calwerstr. 7, 72076 Tuebingen, Germany (Director: Prof. D. Wallwiener);
University of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the eradication rate of endometriosis after surgical resection (SR) vs. thermal ablation with aerosol plasma coagulation (AePC) in a rat model.

methodsIn this prospective, randomized, controlled, single-blinded animal study endometriosis was induced on the abdominal wall of 34 female Wistar rats. After 14 days endometriosis was either removed by SR or ablated by AePC. 14 days later the rats were euthanized to evaluate the eradication rate histopathologically. Intervention times were recorded.

resultsEradication rate of endometriosis after 14 days did not significantly differ between AePC and SR (p=0.22). Intervention time per endometrial lesion was 22.1 s for AePC and 51.8 s for SR (p<0.0001).

conclusionsThis study compares the eradication rate of the new aerosol plasma coagulation device versus standard surgical resection of endometriosis in a rat model. Despite being a thermal method, AePC showed equality towards SR regarding eradication rate but with significantly shorter intervention time.

Indexed as

Abdominal WallAnimalsDisease Models, AnimalEndometriosisFemaleLaser CoagulationProspective StudiesRandom AllocationRats, WistarTreatment Outcomeaerosol plasma coagulationendometriosisnon-contact methodrat modelthermal damage.

Identifiers

PMID26941579
PMCPMC4773283
OpenAlexW2290219283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.