Evidence map›Paper›PMID 26941393›Full record

ReviewGlycobiology2016

Antibody recognition of HIV and dengue glycoproteins.

Isaac J Krauss

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Glycobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Isaac J KraussDepartment of Chemistry, Brandeis University, Waltham, MA 02454, USA kraussi@brandeis.edu.

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
Rational and Combinatorial Design of Immunogens to Elicit 2G12-like AntibodiesR01AI090745 · NIAID · BRANDEIS UNIVERSITY · PI KRAUSS, ISAAC JONATHAN · 2010 to 2022
$3.9M
Design of Immunogens to Elicit PGT122 like AntibodiesR01AI113737 · NIAID · BRANDEIS UNIVERSITY · PI KRAUSS, ISAAC JONATHAN · 2014 to 2018
$2.2M
NIAID NIH HHS R01 AI090745NIAID NIH HHS R01 AI113737NIGMS NIH HHS P41 GM103311
6 · The paper itself

Abstract

The last 6 years have witnessed an explosion of discoveries at the interface of glycobiology and immunology. Binding of clustered oligosaccharides has turned out to be a very frequent mode by which human antibodies have developed broadly neutralizing activity against HIV. This mini-review will cover many recent developments in the HIV antibody field, as well as emerging data about Dengue broadly neutralizing antibodies.

Indexed as

Antibodies, NeutralizingAntibodies, ViralBinding SitesDengueDengue VirusEpitopesHIV-1HIV Envelope Protein gp120HIV InfectionsHumansModels, MolecularProtein BindingProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandProtein Interaction Domains and MotifsViral Envelope ProteinsAntibodies, NeutralizingAntibodies, ViralEpitopesglycoprotein E, dengue virus type 4HIV Envelope Protein gp120Viral Envelope ProteinsDengue broadly neutralizing antibodiesglycoproteinsHIV broadly neutralizing antibodiesmultivalencyprotein–carbohydrate interactions

Identifiers

PMID26941393
PMCPMC5018046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.