Evidence map›Paper›PMID 26941228›Full record

ArticleGenome biology and evolution2016

The Mycobacterium phlei Genome: Expectations and Surprises.

Sarbashis Das, B M Fredrik Pettersson, Phani Rama Krishna Behra, Malavika Ramesh, Santanu Dasgupta, Alok Bhattacharya, Leif A Kirsebom

Open access · goldAbstract read
In one paragraph

Article in Genome biology and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  7. [Rare infectious complication after intramuscular self-injections].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Article
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sarbashis DasDepartment of Cell and Molecular Biology, Box 596, Biomedical Centre, Uppsala, Sweden.
B M Fredrik PetterssonDepartment of Cell and Molecular Biology, Box 596, Biomedical Centre, Uppsala, Sweden.
Phani Rama Krishna BehraDepartment of Cell and Molecular Biology, Box 596, Biomedical Centre, Uppsala, Sweden.
Malavika RameshDepartment of Cell and Molecular Biology, Box 596, Biomedical Centre, Uppsala, Sweden.
Santanu DasguptaDepartment of Cell and Molecular Biology, Box 596, Biomedical Centre, Uppsala, Sweden.
Alok BhattacharyaSchool of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Leif A KirsebomDepartment of Cell and Molecular Biology, Box 596, Biomedical Centre, Uppsala, Sweden leif.kirsebom@icm.uu.se.
Jawaharlal Nehru University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium phlei, a nontuberculosis mycobacterial species, was first described in 1898-1899. We present the complete genome sequence for theM. phlei CCUG21000(T)type strain and the draft genomes for four additional strains. The genome size for all five is 5.3 Mb with 69.4% Guanine-Cytosine content. This is ≈0.35 Mbp smaller than the previously reported M. phlei RIVM draft genome. The size difference is attributed partly to large bacteriophage sequence fragments in theM. phlei RIVM genome. Comparative analysis revealed the following: 1) A CRISPR system similar to Type 1E (cas3) in M. phlei RIVM; 2) genes involved in polyamine metabolism and transport (potAD,potF) that are absent in other mycobacteria, and 3) strain-specific variations in the number of σ-factor genes. Moreover,M. phlei has as many as 82 mce(mammalian cell entry) homologs and many of the horizontally acquired genes in M. phlei are present in other environmental bacteria including mycobacteria that share similar habitat. Phylogenetic analysis based on 693 Mycobacterium core genes present in all complete mycobacterial genomes suggested that its closest neighbor is Mycobacterium smegmatis JS623 and Mycobacterium rhodesiae NBB3, while it is more distant toM. smegmatis mc2 155.

Indexed as

Genome, BacterialAnimalsCRISPR-Cas SystemsGene Transfer, HorizontalGlycerolMycobacterium phleiPhylogenyPolyaminesGlycerolPolyaminescomparative genome analysismycobacterial growthmycobacterial phylogenyMycobacterium phlei genome sequence

Identifiers

PMID26941228
PMCPMC4860684
OpenAlexW2328071476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.