ArticleEuropean heart journal2016
Greater decreases in cholesterol levels among individuals with high cardiovascular risk than among the general population: the northern Sweden MONICA study 1994 to 2014.
Article in European heart journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Incidence, survival, and prevalence trends for myocardial infarction, stroke, hip fracture, and cancer across Swedish birth cohorts: a population-based register study.The Lancet regional health. Europe · 2026Article
- Long-Term Obesity Trends in Northern Sweden: Cross-Sectional Data From the MONICA Study (1986-2022).Obesity science & practice · 2026Article
- Association between atherosclerotic index of plasma and long-term aortic-related adverse events in type B aortic dissection patients undergoing thoracic endovascular aortic repair.Cardiovascular diabetology · 2026Article
- Low carbohydrate high fat-diet in real life; A descriptive analysis of cardiovascular risk factors.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Cohort Profile: The Northern Sweden Health and Disease Study (NSHDS).International journal of epidemiology · 2024Article
- Sauna bathing in northern Sweden: results from the MONICA study 2022.International journal of circumpolar health · 2024Article
- Validation of a digital food frequency questionnaire for the Northern Sweden Diet Database.Nutrition journal · 2024Article
- Prediagnostic markers of insulin resistance and prostate cancer risk and death: A pooled study.Cancer medicine · 2023Article
- Article
- Decreased plasma lipid levels in a statin-free Danish primary health care cohort between 2001 and 2018.Lipids in health and disease · 2021Article
- Waist circumference and a body shape index and prostate cancer risk and mortality.Cancer medicine · 2021Article
- Article
- Lysophospholipids as Predictive Markers of ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI).Metabolites · 2020Article
- Article
- Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium.Lancet (London, England) · 2019Article
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- Article
- The rate of patients at high risk for cardiovascular disease with an optimal low-density cholesterol level: a multicenter study from Thailand.Journal of geriatric cardiology : JGC · 2019Article
- Do cardiovascular disease prevention programs in northern Sweden impact on population health? An interrupted time series analysis.BMC public health · 2019Article
- Sterol 27-Hydroxylase Polymorphism Significantly Associates With Shorter Telomere, Higher Cardiovascular and Type-2 Diabetes Risk in Obese Subjects.Frontiers in endocrinology · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimDecreasing cholesterol levels in Western populations is the main reason for decreasing mortality due to coronary heart disease. Our aim was to analyze trends in cholesterol levels in the population during a period of 20 years in relation to previous cardiovascular disease (CVD), other cardiovascular risk factors, and socioeconomic status. METHODS AND
resultsA total of 4546 women and 4349 men aged 25-74 years participated in five population-based surveys in the Northern Sweden MONICA Study between 1994 and 2014 (participation rate 76.8-62.5%). Total cholesterol levels decreased from 6.2 mmol/L (95% confidence interval, CI, 6.1-6.2) in 1994 to 5.5 mmol/L (CI 5.4-5.5) in 2014. The decrease was more pronounced in elderly vs. younger participants (1.0 vs. 0.5 mmol/L). In 2014, participants with previous CVD, diabetes, or hypertension had lower cholesterol levels than the general population, whereas their levels were higher or similar to the general population in 1994. The use of lipid-lowering drugs increased markedly and was used by 14.3% in 2014. Previously described differences in cholesterol levels between participants with obesity and normal weight, and between those with and without university education, diminished, or vanished over time.
conclusionCholesterol levels decreased by 0.7 mmol/L over 20 years with no sign of abating. The improvement occurred in all age and gender groups but more prominently among those at high risk of ischaemic heart disease.
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