Evidence map›Paper›PMID 26941159›Full record

ArticleGenome announcements2016

Draft Genome Sequences of Two Extensively Drug-Resistant Strains of Mycobacterium tuberculosis Belonging to the Euro-American S Lineage.

Lesibana A Malinga, Thomas Abeel, Christopher A Desjardins, Talent C Dlamini, Gail Cassell, Sinéad B Chapman, Bruce W Birren, Ashlee M Earl, Martie van der Walt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome announcements, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lesibana A MalingaSouth African Medical Research Council TB Platform, Pretoria, Gauteng, South Africa Department of Internal Medicine, University of Pretoria, Pretoria, Gauteng, South Africa lesibana.malinga@mrc.ac.za.
Thomas AbeelBroad Institute, Cambridge, Massachusetts, USA Delft Bioinformatics Laboratory, Delft University of Technology, Delft, The Netherlands.
Christopher A DesjardinsBroad Institute, Cambridge, Massachusetts, USA.
Talent C DlaminiMedical Laboratory Sciences Department, Southern Africa Nazarene University, Manzini, Swaziland.
Gail CassellHarvard Medical School and Infectious Diseases Research Institute, Boston, Massachusetts, USA.
Sinéad B ChapmanBroad Institute, Cambridge, Massachusetts, USA.
Bruce W BirrenBroad Institute, Cambridge, Massachusetts, USA.
Ashlee M EarlBroad Institute, Cambridge, Massachusetts, USA.
Martie van der WaltSouth African Medical Research Council TB Platform, Pretoria, Gauteng, South Africa.

Funding

Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI CUOMO, CHRISTINA A · 2014 to 2024
$66.5M
NIAID NIH HHS HHSN272200900018CNIAID NIH HHS U19 AI110818
6 · The paper itself

Abstract

We report the whole-genome sequencing of two extensively drug-resistant tuberculosis strains belonging to the Euro-American S lineage. The RSA 114 strain showed single-nucleotide polymorphisms predicted to have drug efflux activity.

Identifiers

PMID26941159
PMCPMC4777770

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.