Evidence map›Paper›PMID 26940462›Full record

ReviewInfection2016

A fatal case of disseminated chronic Q fever: a case report and brief review of the literature.

Stephan P Keijmel, Ruud P H Raijmakers, Teske Schoffelen, Maria C W Salet, Chantal P Bleeker-Rovers

Open access · hybridAbstract readCase ReportsReview
In one paragraph

Review in Infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. A systematic review on the health outcomes associated with non-endocarditis manifestations of chronic Q fever.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Pooled it
  2. Article
  3. Virulence · 2021
    Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Stephan P KeijmelDivision of Infectious Diseases 463, Department of Internal Medicine, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. Stephan.Keijmel@radboudumc.nl.
Ruud P H RaijmakersDivision of Infectious Diseases 463, Department of Internal Medicine, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Teske SchoffelenDivision of Infectious Diseases 463, Department of Internal Medicine, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Maria C W SaletDepartment of Pathology, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Chantal P Bleeker-RoversDivision of Infectious Diseases 463, Department of Internal Medicine, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLRadboud Institute for Molecular Life Sciences · NLRadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic Q fever is a rare infection, which mainly manifests as endocarditis, infection of vascular prostheses or aortic aneurysms. We present the case of a 74-year-old immunocompromised man with a haematologically disseminated Coxiella burnetii infection, which has never been reported before. CASE REPORT: He was diagnosed with a chronic Q fever infection of an aneurysm with an endovascular prosthesis in 2015, but he died despite optimal treatment. Autopsy revealed a disseminated C. burnetii infection, confirmed by a positive PCR on samples from several organs. Retrospectively, he already had complaints and signs of inflammation since 2012, for which he had already been admitted in February 2014. At that time, Q fever diagnostics using PCR, complement fixation assay, and enzyme-linked immunosorbent assay on serum were all negative. In retrospect however, retesting available samples from February 2014 using immunofluorescence assay (IFA) already revealed serology compatible with chronic Q fever.

conclusionClinicians should be aware of this silent killer, especially in case of risk factors, and perform an appropriate diagnostic work-up for Q fever including IFA serology and PCR.

Indexed as

AgedAortic Aneurysm, AbdominalBlood Vessel ProsthesisChronic DiseaseComplement Fixation TestsCoxiella burnetiiEnzyme-Linked Immunosorbent AssayFatal OutcomeFluorescent Antibody TechniqueHumansMalePolymerase Chain ReactionQ FeverRisk FactorsThoracic Surgical ProceduresChronic Q feverCoxiella burnetiiDisseminated infectionFatalQ fever

Identifiers

PMID26940462
PMCPMC5042989
OpenAlexW2292597657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.