Evidence map›Paper›PMID 26940262›Full record

ReviewArchives of biochemistry and biophysics2016

Zinc sensing and regulation in yeast model systems.

Stevin Wilson, Amanda J Bird

Abstract readReview
In one paragraph

Review in Archives of biochemistry and biophysics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  6. Conformational dynamics in specialized CProtein science : a publication of the Protein Society · 2025
    Article
  7. Article
  8. Article
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  10. Review
  11. Low-molecular-mass labile metal pools in Escherichia coli: advances using chromatography and mass spectrometry.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2021
    Article
  12. Article
  13. Review
  14. Article
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  16. Insights IntoFrontiers in cellular and infection microbiology · 2020
    Article
  17. Article
  18. Zinc-dependent activation of the Pho8 alkaline phosphatase inThe Journal of biological chemistry · 2019
    Article
  19. Frontiers in microbiology · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stevin WilsonDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA.
Amanda J BirdDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA; Department of Human Sciences, The Ohio State University, Columbus, OH 43210, USA; Center for RNA Biology, The Ohio State University, Columbus, OH 43210, USA. Electronic address: bird.96@osu.edu.
The Ohio State University · US

Funding

Zinc-dependent regulation of gene expressionR01GM105695 · NIGMS · OHIO STATE UNIVERSITY · PI BIRD, AMANDA JANE · 2014 to 2018
$1.4M
NIGMS NIH HHS R01 GM105695
6 · The paper itself

Abstract

The Zap1 transcription factor of Saccharomyces cerevisiae and the Loz1 transcription factor of Schizosaccharomyces pombe both play a central role in zinc homeostasis by controlling the expression of genes necessary for zinc metabolism. Zap1 activates gene expression when cells are limited for zinc, while Loz1 is required for gene repression when zinc is in excess. In this review we highlight what is known about the underlying mechanisms by which these factors are regulated by zinc, and how transcriptional activation and repression in eukaryotic cells can be finely tuned according to intracellular zinc availability.

Indexed as

Gene Expression Regulation, FungalHomeostasisProtein DomainsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSchizosaccharomycesSchizosaccharomyces pombe ProteinsTranscriptional ActivationTranscription FactorsTranscription, GeneticZincZinc FingersLoz1 protein, S pombeSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe ProteinsTranscription FactorsZAP1 protein, S cerevisiaeZincLoz1NutrientTranscriptionYeastZap1Zinc homeostasis

Identifiers

PMID26940262
PMCPMC5010796
OpenAlexW2288366870

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.