Evidence map›Paper›PMID 26940112›Full record

Trial reportBMJ open2016

Feasibility randomised controlled trial of Recovery-focused Cognitive Behavioural Therapy for Older Adults with bipolar disorder (RfCBT-OA): study protocol.

Elizabeth Tyler, Fiona Lobban, Chris Sutton, Colin Depp, Sheri Johnson, Ken Laidlaw, Steven H Jones

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Elizabeth TylerDivision of Health Research, The Spectrum Centre for Mental Health Research, Lancaster University, Lancaster, UK.
Fiona LobbanDivision of Health Research, The Spectrum Centre for Mental Health Research, Lancaster University, Lancaster, UK.
Chris SuttonLancashire Clinical Trials Unit, College of Health and Wellbeing, University of Central Lancashire, Preston, UK.
Colin DeppDepartment of Psychiatry, School of Medicine of the University of California, San Diego, San Diego, California, USA.
Sheri JohnsonDepartment of Psychology, University of California, Berkeley, Berkeley, California, USA.
Ken LaidlawFaculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich, UK.
Steven H JonesDivision of Health Research, The Spectrum Centre for Mental Health Research, Lancaster University, Lancaster, UK.
Lancaster University · GBMental Health Research UK · GBUniversity of California, Berkeley · USUniversity of California, San Diego · USUniversity of Central Lancashire · GBUniversity of East Anglia · GB

Funding

Department of Health DRF-2014-07-094
6 · The paper itself

Abstract

introductionBipolar disorder is a severe and chronic mental health problem that persists into older adulthood. The number of people living with this condition is set to rise as the UK experiences a rapid ageing of its population. To date, there has been very little research or service development with respect to psychological therapies for this group of people. METHODS AND ANALYSIS: A parallel two-arm randomised controlled trial comparing a 14-session, 6-month Recovery-focused Cognitive-Behavioural Therapy for Older Adults with bipolar disorder (RfCBT-OA) plus treatment as usual (TAU) versus TAU alone. Participants will be recruited in the North-West of England via primary and secondary mental health services and through self-referral. The primary objective of the study is to evaluate the feasibility and acceptability of RfCBT-OA; therefore, a formal power calculation is not appropriate. It has been estimated that randomising 25 participants per group will be sufficient to be able to reliably determine the primary feasibility outcomes (eg, recruitment and retention rates), in line with recommendations for sample sizes for feasibility/pilot trials. Participants in both arms will complete assessments at baseline and then every 3 months, over the 12-month follow-up period. We will gain an estimate of the likely effect size of RfCBT-OA on a range of clinical outcomes and estimate parameters needed to determine the appropriate sample size for a definitive, larger trial to evaluate the effectiveness and cost-effectiveness of RfCBT-OA. Data analysis is discussed further in the Analysis section in the main paper. ETHICS AND DISSEMINATION: This protocol was approved by the UK National Health Service (NHS) Ethics Committee process (REC ref: 15/NW/0330). The findings of the trial will be disseminated through peer-reviewed journals, national and international conference presentations and local, participating NHS trusts. TRIAL REGISTRATION NUMBER: ISRCTN13875321; Pre-results.

Indexed as

Research DesignAgedAged, 80 and overBipolar DisorderCognitive Behavioral TherapyCost-Benefit AnalysisEnglandFeasibility StudiesFemaleHumansKaplan-Meier EstimateMaleProportional Hazards ModelsQuality-Adjusted Life YearsQuality of LifeTreatment OutcomeAgeingBipolar DisorderCognitive Behavioural TherapyFeasibilityRandomised Controlled TrialRecovery

Identifiers

PMID26940112
PMCPMC4785318
OpenAlexW2292722555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.