Evidence map›Paper›PMID 26940027›Full record

Trial reportHealth and quality of life outcomes2016

An analysis of the complementarity of ICECAP-A and EQ-5D-3 L in an adult population of patients with knee pain.

T Keeley, J Coast, E Nicholls, N E Foster, S Jowett, H Al-Janabi

Abstract readMulticenter StudyRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Health and quality of life outcomes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Empirical comparison of health-related quality of life and subjective well-being measures in Australian adolescents.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  9. An empirical comparison of sleep-specific versus generic quality of life instruments among Australians with sleep disorders.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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  14. The ICECAP-A instrument for capabilities: assessment of construct validity and test-retest reliability in a general Dutch population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  15. Measurement properties of the ICECAP-A capability well-being instrument among dermatological patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  16. Combining EQ-5D-5L items into a level summary score: demonstrating feasibility using non-parametric item response theory using an international dataset.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  17. Article
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  19. German tariffs for the ICECAP-Supportive Care Measure (ICECAP-SCM) for use in economic evaluations at the end of life.The European journal of health economics : HEPAC : health economics in prevention and care · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

T KeeleyMRC Midland Hub for Trials Methodology Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. t.j.h.keeley@bham.ac.uk.
J CoastSchool of Social and Community Medicine, University of Bristol, Bristol, BS8 2PS, UK.
E NichollsArthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences, Keele University, Keele, Staffordshire, ST5 5BG, UK.
N E FosterArthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences, Keele University, Keele, Staffordshire, ST5 5BG, UK.
S JowettHealth Economics Unit, Institute of Applied Health Research, Public Health Building, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
H Al-JanabiHealth Economics Unit, Institute of Applied Health Research, Public Health Building, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

Funding

Arthritis Research UKDepartment of Health NIHR-RP-011-015Department of Health RP-PG-0407-10386Department of Health RP-PG-1211-20010Medical Research Council G0800808
6 · The paper itself

Abstract

backgroundThe ICECAP measures potentially offer a broader assessment of quality of life and well-being, in comparison to measures routinely used in economic evaluation, such as the EQ-5D-3 L. This broader assessment may allow measurement of the full effects of an intervention or treatment. Previous research has indicated that the ICECAP-O (for older people) and EQ-5D-3 L measure provide complementary information. This paper aims to determine similar information for the ICECAP-A (for the entire adult population) in terms of whether the measure is a substitute or complement to the EQ-5D-3 L.

methodsData from the BEEP trial - a multi-centre, pragmatic, randomised controlled trial - were used. Spearman rank correlations and exploratory factor analytic methods were used to assess whether ICECAP-A and EQ-5D-3 L are measuring the same, or different, constructs.

resultsA correlation of 0.49 (p < 0.01) was found between the ICECAP-A tariff score and the EQ-5D-3 L index. Using the pooled items of the EQ-5D-3 L and the ICECAP-A a two factor solution was optimal, with the majority of EQ-5D-3 L items loading onto one factor and the majority of ICECAP-A items onto another.

conclusionThe results presented in this paper indicate that ICECAP-A and EQ-5D-3 L are measuring two different constructs and provide largely different, complementary information. Results showed a similarity to results presented by Davis et al. using the ICECAP-O.

trial registrationISRCTN 93634563.

Indexed as

KneeAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPainPain MeasurementQuality of LifeSurveys and Questionnaires

Identifiers

PMID26940027
PMCPMC4776364

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.