ArticleAJNR. American journal of neuroradiology2016
Reduced Myelin Water in the White Matter Tracts of Patients with Niemann-Pick Disease Type C.
Article in AJNR. American journal of neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Unveiling Lipid Dysregulation: Lipidomics of Mouse Brain and Isolated Myelin in Niemann-Pick Disease Type C1.bioRxiv : the preprint server for biology · 2026Article
- Harnessing myelin water fraction as an imaging biomarker of human cerebral aging, neurodegenerative diseases, and risk factors influencing myelination: A review.Journal of neurochemistry · 2024Review
- The cholesterol transporter NPC1 is essential for epigenetic regulation and maturation of oligodendrocyte lineage cells.Nature communications · 2023Article
- Chronic oligodendrocyte injury in central nervous system pathologies.Communications biology · 2022Review
- T2-Pseudonormalization and Microstructural Characterization in Advanced Stages of Late-infantile Metachromatic Leukodystrophy.Clinical neuroradiology · 2021Article
- Myelin Defects in Niemann-Pick Type C Disease: Mechanisms and Possible Therapeutic Perspectives.International journal of molecular sciences · 2021Review
- Deregulation of signalling in genetic conditions affecting the lysosomal metabolism of cholesterol and galactosyl-sphingolipids.Neurobiology of disease · 2020Review
- Influence of 7T GRE-MRI Signal Compartment Model Choice on Tissue Parameters.Frontiers in neuroscience · 2020Article
- Myelin water imaging to detect demyelination and remyelination and its validation in pathology.Brain pathology (Zurich, Switzerland) · 2018Review
- Miglustat in Niemann-Pick disease type C patients: a review.Orphanet journal of rare diseases · 2018Review
- Evolution of structural neuroimaging biomarkers in a series of adult patients with Niemann-Pick type C under treatment.Orphanet journal of rare diseases · 2017Article
- Magnetic Resonance of Myelin Water: AnBrain plasticity (Amsterdam, Netherlands) · 2016Review
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Previous studies using diffusion tensor imaging to examine white matter in Niemann-Pick disease type C have produced mixed results. However, diffusion tensor imaging does not directly measure myelin and may be affected by other structural changes. We used myelin water imaging to more directly examine demyelination in 2 patients with Niemann-Pick disease type C. The results suggest that this technique may be useful for identifying regional changes in myelination in this condition.
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Registered trials
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