Evidence map›Paper›PMID 26938428›Full record

ArticleAnalytical chemistry2016

Matrix-Assisted Ionization on a Portable Mass Spectrometer: Analysis Directly from Biological and Synthetic Materials.

Zachary J Devereaux, Christian A Reynolds, Joshua L Fischer, Casey D Foley, Jessica L DeLeeuw, James Wager-Miller, Srinivas B Narayan, Ken Mackie, Sarah Trimpin

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Advances in rapid detection of SARS-CoV-2 by mass spectrometry.Trends in analytical chemistry : TRAC · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Fundamental Studies of New Ionization Technologies and Insights from IMS-MS.Journal of the American Society for Mass Spectrometry · 2019
    Article
  11. Strengths and Weaknesses of Molecular Simulations of Electrosprayed Droplets.Journal of the American Society for Mass Spectrometry · 2018
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Zachary J DevereauxDepartment of Chemistry, Wayne State University , 5101 Cass Avenue, Detroit, Michigan 48202, United States.
Christian A ReynoldsDepartment of Chemistry, Wayne State University , 5101 Cass Avenue, Detroit, Michigan 48202, United States.
Joshua L FischerDepartment of Chemistry, Wayne State University , 5101 Cass Avenue, Detroit, Michigan 48202, United States.
Casey D FoleyDepartment of Chemistry, Wayne State University , 5101 Cass Avenue, Detroit, Michigan 48202, United States.
Jessica L DeLeeuwDepartment of Chemistry, Wayne State University , 5101 Cass Avenue, Detroit, Michigan 48202, United States.
James Wager-MillerGill Center for Biomolecular Science, Indiana University , 702 N. Walnut Grove Avenue, Bloomington, Indiana 47405, United States.
Srinivas B NarayanDetroit Medical Center: Detroit Hospital, 4201 St. Antoine Street, Detroit, Michigan 48201, United States.
Ken MackieGill Center for Biomolecular Science, Indiana University , 702 N. Walnut Grove Avenue, Bloomington, Indiana 47405, United States.
Sarah TrimpinDepartment of Chemistry, Wayne State University , 5101 Cass Avenue, Detroit, Michigan 48202, United States.
Wayne State University · USDetroit Medical Center · USEugene O'Neill Theater Center · USIndiana University Bloomington · US

Funding

Neuronal cannabinoidsR01DA011322 · NIDA · UNIVERSITY OF WASHINGTON · PI MACKIE, KENNETH · 1998 to 2014
$3.4M
Cannabinoid Modulation of Cell FunctionK05DA021696 · NIDA · TRUSTEES OF INDIANA UNIVERSITY · PI MACKIE, KENNETH · 2007 to 2017
$1.3M
NIDA NIH HHS K05 DA021696NIDA NIH HHS R01 DA011322
6 · The paper itself

Abstract

Matrix-assisted ionization (MAI)-mass spectrometry (MS) eliminates the need for high voltage, a heat source, lasers, and compressed gases in the ionization process and uses minimal solvents in sample preparation, thus making MAI ideal for field-portable mass spectrometers. The broad applicability of MAI is demonstrated by simple, rapid, and robust positive and negative detection mode analyses of low and high mass compounds including some pesticides, dyes, drugs, lipids, and proteins (186 Da to 8.5 kDa) from various materials including urine, biological tissue sections, paper, and plant material on a low pumping capacity, single-quadrupole mass spectrometer. Different sample introduction methods are applicable, including the use of a pipet tip or glass melting point tube, allowing integration of sample preparation with sample introduction for increased analytical utility and ease of operation, even when sampling directly from surfaces.

Indexed as

Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationColoring AgentsLipidsPesticidesPharmaceutical PreparationsProteinsColoring AgentsLipidsPesticidesPharmaceutical PreparationsProteins

Identifiers

PMID26938428
PMCPMC10614167
OpenAlexW2290816085

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.