Evidence map›Paper›PMID 26938364›Full record

SynthesisNursing research

Overall Adiposity, Adipose Tissue Distribution, and Endometriosis: A Systematic Review.

Uba Backonja, Germaine M Buck Louis, Diane R Lauver

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Nursing research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Kisspeptin and Endometriosis-Is There a Link?Journal of clinical medicine · 2024
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. What is the link between endometriosis and adiposity?Obstetrics & gynecology science · 2022
    Article
  16. Review
  17. Article
  18. The evolutionary biology of endometriosis.Evolution, medicine, and public health · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Uba BackonjaUba Backonja, PhD, RN, is National Library of Medicine Biomedical Informatics Postdoctoral Fellow, Department of Biomedical Informatics and Medical Education, University of Washington School of Medicine, Seattle. Germaine M. Buck Louis, PhD, MS, is Director and Senior Investigator, Office of the Director, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, Maryland. Diane R. Lauver, PhD, RN, FAAN, is Professor, School of Nursing, University of Wisconsin-Madison.
Germaine M Buck Louis
Diane R Lauver
Apple (Israel) · IL

Funding

University of Washington Biomedical Informatics and Data Science Research Training ProgramT15LM007442 · NLM · UNIVERSITY OF WASHINGTON · PI JOHN H. GENNARI, Andrea L. Hartzler · 2002 to 2026
$19.6M
ENDO Study: Endometriosis, Natural History and DiagnosisZIAHD008829 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI CHEN, ZHEN · 2009 to 2021
$741k
NLM NIH HHS T15 LM007442NLM NIH HHS T15LM007442
6 · The paper itself

Abstract

backgroundEndometriosis has been associated with a lean body habitus. However, we do not understand whether endometriosis is also associated with other characteristics of adiposity, including adipose tissue distribution and amount of visceral adipose tissue (VAT; adipose tissue lining inner organs). Having these understandings may provide insights on how endometriosis develops-some of the physiological actions of adipose tissue differ depending on tissue amount and location and are related to proposed mechanisms of endometriosis development.

objectivesThe aim of this study was to review the literature regarding overall adiposity, adipose tissue distribution and/or VAT, and endometriosis.

methodsWe reviewed and synthesized studies indexed in PubMed and/or Web of Science. We included studies that had one or more measures of overall adiposity, adipose tissue distribution, and/or VAT and women with and without endometriosis for comparison. We summarized the findings and commented on the methods used and potential sources of bias.

resultsOf 366 identified publications, 19 (5.2%) were eligible. Two additional publications were identified from reference lists. Current research included measures of overall adiposity (e.g., body figure drawings) or adipose tissue distribution (e.g., waist-to-hip ratio), but not VAT. The weight of evidence indicated that endometriosis was associated with low overall adiposity and with a preponderance of adipose tissue distributed below the waist (peripheral). DISCUSSION: Endometriosis may be associated with being lean or having peripherally distributed adipose tissue. Well-designed studies with various sampling frameworks and precise measures of adiposity and endometriosis are needed to confirm associations between adiposity measures and endometriosis and delineate potential etiological mechanisms underlying endometriosis.

Indexed as

AdiposityEndometriosisFemaleHumansIntra-Abdominal Fat

Identifiers

PMID26938364
PMCPMC4780367
OpenAlexW2319146733

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.