ArticleMedicine2016
A Retrospective Case-Series of Children With Bone and Joint Infection From Northern Australia.
Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Pooled it
- Berrembi Jarragboo-Boorroo Wajawoorroo Men'Gawoom Gijam (Gija Healthy Skin Story): Two-Way Learning for Healthy Skin.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2025Trial
- Clinical characteristics, pathogenesis, treatment, and prognosis of bone and joint infections in neonates: a single-center report of 20 cases.BMC pediatrics · 2026Article
- Article
- Management and Outcomes of Paediatric Bone and Joint Infections in a Regional Australian Hospital: A 10-Year Retrospective Study.Journal of paediatrics and child health · 2026Article
- Pan-PCR Diagnostic Efficacy in Comparison with Traditional Methods in Patients with Septic Arthritis.Iranian journal of pathology · 2026Article
- Osteomyelitis and Septic Arthritis of the Upper Extremity in Pediatric Patients.Current reviews in musculoskeletal medicine · 2025Review
- Article
- Analysis of antimicrobial resistance and clinical features of Staphylococcus aureus-infected bone and joint infections in children.BMC pediatrics · 2025Article
- Ethical bioprospecting and microbial assessments for sustainable solutions to the AMR crisis.IUBMB life · 2025Review
- Osteomyelitis and Septic Arthritis in the Darwin Prospective Melioidosis Study.Open forum infectious diseases · 2025Article
- SPA inhibits hBMSC osteogenic differentiation and M1 macrophage polarization by suppressing SETD2 in acute suppurative osteomyelitis.Scientific reports · 2024Article
- Clinical outcomes of pediatric osteomyelitis.BMC pediatrics · 2023Article
- Is Early Surgical Intervention Necessary for Acute Neonatal Humeral Epiphyseal Osteomyelitis: A Retrospective Study of 31 Patients.Children (Basel, Switzerland) · 2022Article
- The Epidemiology of Osteomyelitis in Children.Children (Basel, Switzerland) · 2021Article
- Acute osteoarticular infections in children are frequently forgotten multidiscipline emergencies: beyond the technical skills.EFORT open reviews · 2021Review
- Skin infections in Australian Aboriginal children: a narrative review.The Medical journal of Australia · 2020Review
- Article
- Article
- Diagnosis and management of acute osteoarticular infections in children.Paediatrics & child health · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our clinical workload as infectious diseases pediatricians in northern Australia is dominated by complicated bone and joint infections in indigenous children. We reviewed the clinical presentation, microbiology, management, and outcomes of children presenting to Royal Darwin Hospital with bone and joint infections between 2010 and 2013, and aimed to compare severity and incidence with other populations worldwide.A retrospective audit was performed on children aged 0 to 18 years who were admitted to Royal Darwin Hospital between 1 January 2010 and 31 December 2013 with a bone and joint infection.Seventy-nine patients were identified, of whom 57 (72%) had osteomyelitis ± associated septic arthritis and 22 (28%) had septic arthritis alone. Sixty (76%) were indigenous Australians. The incidence rate of osteomyelitis for indigenous children was 82 per 100,000 children. Staphylococcus aureus was the confirmed pathogen in 43/79 (54%), of which 17/43 (40%) were methicillin resistant. Median length of stay was 17 days (interquartile range: 10-31 days) and median length of IV antibiotics was 15 days (interquartile range: 6-24 days). Fifty-six (71%) required at least 1 surgical procedure. Relapse within 12 months was documented in 12 (15%) patients.We report 3 key findings: osteomyelitis incidence in indigenous children of northern Australia is amongst the highest reported in the world; methicillin-resistant S aureus accounts for 36% of osteomyelitis with a positive microbiological diagnosis; and the severity of disease requires extended antibiotic therapy. Despite this, 15% of the cohort relapsed within 12 months and required readmission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.