ReviewApplied & translational genomics2015
Neurogenomics: An opportunity to integrate neuroscience, genomics and bioinformatics research in Africa.
Review in Applied & translational genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Review
- The Potential of Bioinformatics in Revolutionizing Disease Diagnosis in Sub-Saharan Africa: A Narrative Review.Health science reports · 2026Article
- Genetic Neuromuscular Disorders and Health Services Access, Utilization, and Needs in Zambia.Pediatric neurology · 2023Article
- Neurogenomics in Africa: current state, challenges, opportunities, and recommendation.Annals of medicine and surgery (2012) · 2023Article
- Neuroscience education and research in Cameroon: Current status and future direction.IBRO neuroscience reports · 2021Article
- Article
- Think: Theory for Africa.PLoS computational biology · 2019Article
- Transcriptional and Genomic Targets of Neural Stem Cells for Functional Recovery after Hemorrhagic Stroke.Stem cells international · 2017Review
- Notes on the Recent History of Neuroscience in Africa.Frontiers in neuroanatomy · 2017Review
- Disregard of neurological impairments associated with neglected tropical diseases in Africa.eNeurologicalSci · 2016Article
- Neuroscience-related research in Ghana: a systematic evaluation of direction and capacity.Metabolic brain disease · 2016Review
- Building sustainable neuroscience capacity in Africa: the role of non-profit organisations.Metabolic brain disease · 2016Review
- Developing expertise in bioinformatics for biomedical research in Africa.Applied & translational genomics · 2015Article
- Bioinformatics in Africa: The Rise of Ghana?PLoS computational biology · 2015Article
- Widening participation would be key in enhancing bioinformatics and genomics research in Africa.Applied & translational genomics · 2015Article
- Neurogenomics: Challenges and opportunities for Ghana.Applied & translational genomics · 2015Article
- Motor Neuron Diseases in Sub-Saharan Africa: The Need for More Population-Based Studies.BioMed research international · 2015Review
- The African Initiative for Bioinformatics Online Training in Neurodegenerative Diseases (AI-BOND): Investing in the next generation of African neuroscientists.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modern genomic approaches have made enormous contributions to improving our understanding of the function, development and evolution of the nervous system, and the diversity within and between species. However, most of these research advances have been recorded in countries with advanced scientific resources and funding support systems. On the contrary, little is known about, for example, the possible interplay between different genes, non-coding elements and environmental factors in modulating neurological diseases among populations in low-income countries, including many African countries. The unique ancestry of African populations suggests that improved inclusion of these populations in neuroscience-related genomic studies would significantly help to identify novel factors that might shape the future of neuroscience research and neurological healthcare. This perspective is strongly supported by the recent identification that diseased individuals and their kindred from specific sub-Saharan African populations lack common neurological disease-associated genetic mutations. This indicates that there may be population-specific causes of neurological diseases, necessitating further investigations into the contribution of additional, presently-unknown genomic factors. Here, we discuss how the development of neurogenomics research in Africa would help to elucidate disease-related genomic variants, and also provide a good basis to develop more effective therapies. Furthermore, neurogenomics would harness African scientists' expertise in neuroscience, genomics and bioinformatics to extend our understanding of the neural basis of behaviour, development and evolution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.