Evidence map›Paper›PMID 26937321›Full record

ArticleGlobal advances in health and medicine2016

Improvement of Asthma and Gastroesophageal Reflux Disease With Oral Pulvis stomachicus cum Belladonna, a Combination of Matricaria recutita, Atropa belladonna, Bismuth, and Antimonite: A Pediatric Case Report.

Tido von Schoen-Angerer, René Madeleyn, Helmut Kiene, Gunver S Kienle, Jan Vagedes

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Global advances in health and medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Alternative Treatments for Minor GI Ailments.Innovations in pharmacy · 2019
    Review
  4. Journal of pharmacy & bioallied sciences
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Tido von Schoen-AngererARCIM Institute, Filderklinik, Filderstadt, Germany; Department of Pediatrics, Fribourg Hospital HFR, Switzerland (Dr von Schoen-Angerer).
René MadeleynDepartment of Pediatrics, Filderklinik, Filderstadt, Germany (Dr Madeleyn).
Helmut KieneInstitute for Applied Epistemology and Medical Methodology, University of Witten/Herdecke, Freiburg, Germany (Dr Kiene).
Gunver S KienleInstitute for Applied Epistemology and Medical Methodology, University of Witten/Herdecke, Freiburg, Germany (Dr Kienle).
Jan VagedesARCIM Institute, Filderklinik, Filderstadt, Germany; Department of Pediatrics, University Hospital, Tübingen, Germany (Dr Vagedes).
Academic Research in Complementary and Integrative Medicine · DEKarl Schlecht Stiftung · DEUniversity Children's Hospital Tübingen · DEWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between gastroesophageal reflux disease (GERD) and asthma, although well established in adults, is less strong in the pediatric age group. Benefits of proton pump therapy are limited across age ranges. While there is a growing body of literature on the use of complementary treatments for both asthma and GERD, few studies have focused on treatment benefits for the GERD-asthma association. We present the case of a 2-year-old boy with asthma and GERD who was not responding to inhaled, low-dose corticosteroids, beta-mimetic therapy, and a 6-week course of proton pump inhibitor treatment. We noted a gradual disappearance of symptoms when he was given an oral preparation of Pulvis stomachicus cum Belladonna, an anthroposophic medication containing Matricaria recutita, Atropa belladonna, bismuth, and antimonite. Matricaria recutita and bismuth have known gastric protective properties, and Atropa belladonna contains anticholinergic agents that have a bronchodilatory effect. These complementary medications appear promising in terms of relieving the symptoms of GERD-associated asthma.

Indexed as

anthroposophic medicineAsthmaAtropa belladonnacomplementary medicinegastroesophageal reflux diseaseMatricaria recutitaPulvis stomachicus cum Belladonna

Identifiers

PMID26937321
PMCPMC4756774
OpenAlexW2234284275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.