Evidence map›Paper›PMID 26936966›Full record

ArticleThe Journal of international medical research2016

Factors correlated with the resolution of macular oedema after one dose injection of intravitreal triamcinolone acetonide treatment in branch retinal vein occlusion.

Shuang Zhang, Ningyu An, Wenjing Ha, Shaochi Zhang, Xiaowen Hu, Aihua Ma, Bojun Zhao

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shuang ZhangDepartment of Ophthalmology, Shandong Provincial Hospital affiliated to Shandong University, Jinan, Shandong Province, China Department of Ophthalmology, Ningxia Eye Hospital, Ningxia People's Hospital, Yinchuan, Ningxia, China.
Ningyu AnDepartment of Ophthalmology, Ningxia Eye Hospital, Ningxia People's Hospital, Yinchuan, Ningxia, China.
Wenjing HaDepartment of Ophthalmology, Ningxia Eye Hospital, Ningxia People's Hospital, Yinchuan, Ningxia, China.
Shaochi ZhangDepartment of Ophthalmology, Ningxia Eye Hospital, Ningxia People's Hospital, Yinchuan, Ningxia, China.
Xiaowen HuDepartment of Ophthalmology, Ningxia Eye Hospital, Ningxia People's Hospital, Yinchuan, Ningxia, China.
Aihua MaDepartment of Paediatrics, Shandong Provincial Hospital affiliated to Shandong University, Jinan, Shandong Province, China aihuama@hotmail.co.uk.
Bojun ZhaoDepartment of Ophthalmology, Shandong Provincial Hospital affiliated to Shandong University, Jinan, Shandong Province, China zhaobojun@hotmail.com.
Ningxia Hui Autonomous Region Peoples Hospital · CNShandong Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the predictive baseline factors for a successful outcome following one dose of intravitreal triamcinolone acetonide (IVTA) in patients with macular oedema (ME) caused by branch retinal vein occlusion (BRVO).

methodsThis retrospective study enrolled patients with ME (macular retinal thickness [MRT] ≥ 300 µm) due to BRVO who still had ME 3 months after grid laser photocoagulation. Patients were divided according to treatment into an IVTA group and a laser-only group. The resolution of ME was documented at months 3 and 6.

resultsA total of 154 eyes with ME were investigated: IVTA group (90 eyes) and laser-only group (64 eyes). Predictive factors for successful IVTA treatment were younger age, shorter duration of ME, initial onset ME, accompanied by serous retinal detachment, few concomitant systemic diseases and nonischaemic BRVO. A broken foveal capillary ring was related to a poor treatment outcome. Eyes with cystoid spaces in the outer plexiform layer were more likely to have a good treatment response.

conclusionIVTA is effective for resolving ME due to BRVO after grid laser photocoagulation treatment.

Indexed as

DemographyDose-Response Relationship, DrugFemaleHumansIntravitreal InjectionsLight CoagulationMacular EdemaMaleMiddle AgedRecurrenceRetinal Vein OcclusionTreatment OutcomeTriamcinolone AcetonideTriamcinolone AcetonideBranch retinal vein occlusionintravitreal injectionmacular oedemamorphologytriamcinolone acetonide

Identifiers

PMID26936966
PMCPMC5536696
OpenAlexW2330752784

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.