Evidence map›Paper›PMID 26936842›Full record

Trial reportEuropean journal of nutrition2017

Wine consumption reduced postprandial platelet sensitivity against platelet activating factor in healthy men.

Marianna N Xanthopoulou, Konstantia Kalathara, Sophia Melachroinou, Kalliopi Arampatzi-Menenakou, Smaragdi Antonopoulou, Mary Yannakoulia, Elizabeth Fragopoulou

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03603769 (In Vitro And Ex Vivo Anti-Inflammatory Activities Of Salmon Polar Lipids), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03603769 nacompletednot on this mapstarted 2018, after this paper: background citation

In Vitro And Ex Vivo Anti-Inflammatory Activities Of Salmon Polar Lipids

TypeinterventionalSponsorUniversity of LimerickRan2018 to 2019Enrolled6ConditionsCardiovascular DiseasesArmsFood supplement capsules containing Salmon-Polar Lipids, Placebo food supplement capsule
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Review
  6. Article
  7. Review
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  10. [Correlational study on portal vein thrombosis of liver cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2020
    Article
  11. Review
  12. Review
  13. Review
  14. Review
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  17. Wine Flavonoids in Health and Disease Prevention.Molecules (Basel, Switzerland) · 2017
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marianna N XanthopoulouDepartment of Nutrition and Dietetics, Harokopio University, 70 Eleftheriou Venizelou Avenue Kallithea, 17671, Athens, Greece.
Konstantia KalatharaDepartment of Nutrition and Dietetics, Harokopio University, 70 Eleftheriou Venizelou Avenue Kallithea, 17671, Athens, Greece.
Sophia MelachroinouDepartment of Nutrition and Dietetics, Harokopio University, 70 Eleftheriou Venizelou Avenue Kallithea, 17671, Athens, Greece.
Kalliopi Arampatzi-MenenakouDepartment of Nutrition and Dietetics, Harokopio University, 70 Eleftheriou Venizelou Avenue Kallithea, 17671, Athens, Greece.
Smaragdi AntonopoulouDepartment of Nutrition and Dietetics, Harokopio University, 70 Eleftheriou Venizelou Avenue Kallithea, 17671, Athens, Greece.
Mary YannakouliaDepartment of Nutrition and Dietetics, Harokopio University, 70 Eleftheriou Venizelou Avenue Kallithea, 17671, Athens, Greece.
Elizabeth FragopoulouDepartment of Nutrition and Dietetics, Harokopio University, 70 Eleftheriou Venizelou Avenue Kallithea, 17671, Athens, Greece. efragop@hua.gr.
Harokopio University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePlatelet activating factor (PAF) is a potent inflammatory and thrombotic mediator that participates in the initiation and prolongation of atherosclerosis. The aim of the present study was to evaluate the potential effect of wine consumption on platelet aggregation against PAF.

methodsThe study had cross-over design. Ten healthy men participated in four daily trials on separate days: They consumed a standardized meal along with white wine, Robola variety (trial R), or red wine, Cabernet Sauvignon variety (trial CS), or an ethanol solution (trial E), or water (trial W). Blood samples were collected before and after meal consumption and at several time points during the next 6 h. Platelet aggregation against PAF (EC

resultsA significant trial effect was found in platelet sensitivity against PAF (p

conclusionsWine consumption improved platelet sensitivity independently of alcohol, kept triacylglycerols at lower levels during their postprandial elevation, and did not affect plasminogen activator inhibitor-1 levels more adversely than ethanol per se.

Indexed as

Platelet AggregationPostprandial PeriodWineAdultAtherosclerosisBiomarkersBlood PlateletsBody Mass IndexBody WeightCholesterolCross-Over StudiesHumansMalePlasminogen Activator Inhibitor 1Platelet Activating FactorPlatelet Aggregation InhibitorsBiomarkersCholesterolPlasminogen Activator Inhibitor 1Platelet Activating FactorPlatelet Aggregation InhibitorsSERPINE1 protein, humanTriglyceridesAlcoholInflammationMicroconstituentsPhenolic compoundsPostprandialThrombosis

Identifiers

PMID26936842
OpenAlexW2292511334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.