ArticleHuman brain mapping2016
White matter microstructure and impulsivity in methamphetamine dependence with and without a history of psychosis.
Article in Human brain mapping, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Dropout Rates in Psychosocial Interventions for People With Both Severe Mental Illness and Substance Misuse: A Systematic Review and Meta-Analysis.Frontiers in psychiatry · 2022Pooled it
- A meta-analysis of tract-based spatial statistics studies examining white matter integrity in cocaine use disorder.Addiction biology · 2021Pooled it
- Imaging neuroinflammation in individuals with substance use disorders.The Journal of clinical investigation · 2024Review
- Non-local diffusion-based biomarkers in patients with cocaine use disorder.Neuroimage. Reports · 2024Article
- Impulsivity in amphetamine use disorder: Examination of sex differences.Addiction (Abingdon, England) · 2023Article
- Beyond BMI: cardiometabolic measures as predictors of impulsivity and white matter changes in adolescents.Brain structure & function · 2023Article
- Association between white matter microstructure and cognitive function in patients with methamphetamine use disorder.Human brain mapping · 2023Article
- Assessing the mediating role of impulsivity between methamphetamine-induced psychotic disorders and increased gambling severity in methamphetamine-dependent individuals.European archives of psychiatry and clinical neuroscience · 2022Article
- White matter microstructure differences in individuals with dependence on cocaine, methamphetamine, and nicotine: Findings from the ENIGMA-Addiction working group.Drug and alcohol dependence · 2022Article
- Common gray matter loss in the frontal cortex in patients with methamphetamine-associated psychosis and schizophrenia.NeuroImage. Clinical · 2022Article
- Cerebral microstructural abnormalities in impulsivity: a magnetic resonance study.Brain imaging and behavior · 2021Article
- Elevated thalamic glutamate levels and reduced water diffusivity in alcohol use disorder: Association with impulsivity.Psychiatry research. Neuroimaging · 2020Article
- Neuroanatomical correlates of impulsive traits in children aged 9 to 10.Journal of abnormal psychology · 2020Article
- White Matter Abnormalities Based on TBSS and Its Correlation With Impulsivity Behavior of Methamphetamine Addicts.Frontiers in psychiatry · 2020Article
- A comparison of regional brain volumes and white matter connectivity in subjects with stimulant induced psychosis versus schizophrenia.Psychopharmacology · 2019Observational
- Cognition and Related Neural Findings on Methamphetamine Use Disorder: Insights and Treatment Implications From Schizophrenia Research.Frontiers in psychiatry · 2019Review
- Gut microbiome populations are associated with structure-specific changes in white matter architecture.Translational psychiatry · 2018Article
- Molecular, Behavioral, and Physiological Consequences of Methamphetamine Neurotoxicity: Implications for Treatment.The Journal of pharmacology and experimental therapeutics · 2017Review
- Altered microstructure rather than morphology in the corpus callosum after lower limb amputation.Scientific reports · 2017Article
- Parallel changes in serum proteins and diffusion tensor imaging in methamphetamine-associated psychosis.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMethamphetamine (MA) use may lead to white matter injury and to a range of behavioral problems and psychiatric disorders, including psychosis. The present study sought to assess white matter microstructural impairment as well as impulsive behavior in MA dependence and MA-associated psychosis (MAP).
methodsThirty patients with a history of MAP, 39 participants with MA dependence and 40 healthy controls underwent diffusion tensor imaging (DTI). Participants also completed the UPPS-P impulsive behavior questionnaire. We applied tract-based spatial statistics (TBSS) to investigate group differences in mean diffusivity (MD), fractional anisotropy (FA), axial (λ‖ ) and radial diffusivity (λ⊥ ), and their association with impulsivity scores and psychotic symptoms.
resultsThe MAP group displayed widespread higher MD, λ‖ and λ⊥ levels compared to both controls and the MA group, and lower FA in extensive white matter areas relative to controls. MD levels correlated positively with negative psychotic symptoms in MAP. No significant DTI group differences were found between the MA group and controls. Both clinical groups showed high levels of impulsivity, and this dysfunction was associated with DTI measures in frontal white matter tracts.
conclusionsMAP patients show distinct patterns of impaired white matter integrity of global nature relative to controls and the MA group. Future work to investigate the precise nature and timing of alterations in MAP is needed. The results are further suggestive of frontal white matter pathology playing a role in impulsivity in MA dependence and MAP. Hum Brain Mapp 37:2055-2067, 2016. © 2016 Wiley Periodicals, Inc.
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