Evidence map›Paper›PMID 26936601›Full record

Trial reportSurgical endoscopy2016

Perioperative immunonutrition in normo-nourished patients undergoing laparoscopic colorectal resection.

Pedro Moya, Elena Miranda, Leticia Soriano-Irigaray, Antonio Arroyo, Maria-Del-Mar Aguilar, Marta Bellón, Jose-Luis Muñoz, Fernando Candela, Rafael Calpena

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 15 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 15 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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  14. Effect of Perioperative Nutritional Supplementation on Postoperative Complications-Systematic Review and Meta-Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Pedro MoyaDepartment of Surgery and Pathology, University Miguel Hernandez of Elche, Elche, Spain. pedromoyaforcen@gmail.com.
Elena MirandaDepartment of Anaesthesia, University General Hospital of Elche, Elche, Spain.
Leticia Soriano-IrigarayDepartment of Surgery and Pathology, University Miguel Hernandez of Elche, Elche, Spain.
Antonio ArroyoDepartment of Surgery and Pathology, University Miguel Hernandez of Elche, Elche, Spain.
Maria-Del-Mar AguilarDivision of Colorectal Surgery, Department of General Surgery, University General Hospital of Elche, Elche, Spain.
Marta BellónDivision of Colorectal Surgery, Department of General Surgery, University General Hospital of Elche, Elche, Spain.
Jose-Luis MuñozDepartment of Anaesthesia, University General Hospital of Elche, Elche, Spain.
Fernando CandelaDepartment of Surgery and Pathology, University Miguel Hernandez of Elche, Elche, Spain.
Rafael CalpenaDepartment of Surgery and Pathology, University Miguel Hernandez of Elche, Elche, Spain.
Hospital General Universitario de Elche · ESUniversitat de Miguel Hernández d'Elx · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether the joint implementation of immunonutrition and a laparoscopic approach improves morbidity, mortality, and length of stay (LOS) compared with dietary advice.

backgroundDespite progress in recent years in the surgical management of patients with colorectal cancer, postoperative complications are frequent. Nutritional supplements enriched with immunonutrients have recently been introduced into clinical practice. However, the immunonutrition benefits in patients undergoing colorectal laparoscopic surgery are unknown.

methodsThis study was a prospective, randomized trial with two parallel treatment groups receiving an immune-enhancing dietary supplement for 7 days before colorectal resection and 5 days postoperatively or dietary advice.

resultsA total of 128 patients were randomized. At baseline, both groups were comparable with respect to age, sex, surgical risk, comorbidities, and analytical and nutritional parameters. The median postoperative LOS was 5 days and was not significantly different between the groups. Wound infection differed significantly between the groups (11.50 vs. 0.00 %, p = 0.006). No other differences between the groups were identified.

conclusionsThe joint use of laparoscopy and supplementation with immunonutrients reduces surgical wound infection in patients undergoing colorectal surgery.

trial registrationThis study is registered with ClinicalTrial.gov : NCT0239396.

Indexed as

Dietary SupplementsLaparoscopyPerioperative CareAgedAged, 80 and overColectomyColorectal NeoplasmsEnteral NutritionFemaleHumansLength of StayMaleMiddle AgedPatient ReadmissionProspective StudiesSurgical Wound InfectionImmunonutritionLaparoscopicSurgical complication

Identifiers

PMID26936601
OpenAlexW2289789973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.