Evidence map›Paper›PMID 26936475›Full record

ArticleEnvironmental science and pollution research international2016

β-Estradiol and ethinyl-estradiol contamination in the rivers of the Carpathian Basin.

Péter Avar, Zita Zrínyi, Gábor Maász, Anikó Takátsy, Sándor Lovas, László G-Tóth, Zsolt Pirger

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Biodegradation and Metabolic Pathway of 17β-Estradiol byInternational journal of molecular sciences · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Thermal baths as sources of pharmaceutical and illicit drug contamination.Environmental science and pollution research international · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Péter AvarDepartment of Analytical Biochemistry, Institute of Biochemistry and Medical Chemistry, University of Pécs, Pécs, 7624, Hungary. peter.avar@aok.pte.hu.
Zita ZrínyiAdaptive Neuroethology, Department of Experimental Zoology, Tihany, 8237, Hungary.
Gábor MaászDepartment of Analytical Biochemistry, Institute of Biochemistry and Medical Chemistry, University of Pécs, Pécs, 7624, Hungary.
Anikó TakátsyDepartment of Analytical Biochemistry, Institute of Biochemistry and Medical Chemistry, University of Pécs, Pécs, 7624, Hungary.
Sándor LovasAdaptive Neuroethology, Department of Experimental Zoology, Tihany, 8237, Hungary.
László G-TóthDepartment of Hydrozoology, Balaton Limnological Institute, MTA Centre for Ecological Research, Tihany, 8237, Hungary.
Zsolt PirgerAdaptive Neuroethology, Department of Experimental Zoology, Tihany, 8237, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

17β-Estradiol (E2) and 17α-ethinyl estradiol (EE2), which are environmental estrogens, have been determined with LC-MS in freshwater. Their sensitive analysis needs derivatization and therefore is very hard to achieve in multiresidue screening. We analyzed samples from all the large and some small rivers (River Danube, Drava, Mur, Sava, Tisza, and Zala) of the Carpathian Basin and from Lake Balaton. Freshwater was extracted on solid phase and derivatized using dansyl chloride. Separation was performed on a Kinetex XB-C18 column. Detection was achieved with a benchtop orbitrap mass spectrometer using targeted MS analysis for quantification. Limits of quantification were 0.05 ng/L (MS1) and 0.1 ng/L (MS/MS) for E2, and 0.001 ng/L (MS1) and 0.2 ng/L (MS/MS) for EE2. River samples contained n.d.-5.2 ng/L E2 and n.d.-0.68 ng/L EE2. Average levels of E2 and EE2 were 0.61 and 0.084 ng/L, respectively, in rivers, water courses, and Lake Balaton together, but not counting city canal water. EE2 was less abundant, but it was still present in almost all of the samples. In beach water samples from Lake Balaton, we measured 0.076-0.233 E2 and n.d.-0.133 EE2. A relative high amount of EE2 was found in river Zala (0.68 ng/L) and in Hévíz-Páhoki canal (0.52 ng/L), which are both in the catchment area of Lake Balaton (Hungary).

Indexed as

Chromatography, LiquidEnvironmental MonitoringEstradiolEstrogensEthinyl EstradiolHungaryLakesRiversTandem Mass SpectrometryWater Pollutants, ChemicalEstradiolEstrogensEthinyl EstradiolWater Pollutants, ChemicalEstrogenEthinyl estradiolFreshwaterRiverSteroidβ-Estradiol

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.