ArticleCurrent pain and headache reports2016
Childhood Maltreatment and Headache Disorders.
Article in Current pain and headache reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 44 citations in OpenAlex.
- Article
- Benefit of Dietary Supplementation of Nutraceuticals as an Integrative Approach for Management of Migraine: Evidence From Preclinical and Clinical Studies.Current pain and headache reports · 2024Review
- Medication Overuse Headache: an Updated Review and Clinical Recommendations on Management.Current neurology and neuroscience reports · 2023Review
- Social cognition in chronic migraine with medication overuse: a cross-sectional study on different aspects of mentalization and social relationships.The journal of headache and pain · 2023Article
- Tension-Type Headache in Children and Adolescents.Life (Basel, Switzerland) · 2023Review
- The Psychiatric Comorbidities of Migraine in Children and Adolescents.Current pain and headache reports · 2021Review
- Associations between adverse childhood experiences and migraine among teenage mothers in Peru.Journal of psychosomatic research · 2021Article
- Neuroprotective Effect of Enriched Chicken Bone Broth as a Dietary Supplement in a Model of Migraine Mediated by Early Life Stress.Journal of medicinal food · 2020Article
- Adverse childhood experience and adult persistent pain and disability: protocol for a systematic review and meta-analysis.Systematic reviews · 2020Article
- When a Head Is about to Burst: Attachment Mediates the Relationship Between Childhood Trauma and Migraine.International journal of environmental research and public health · 2020Article
- The Relationship Between Migraine or Severe Headache and Chronic Health Conditions: A Cross-Sectional Study from the National Health Interview Survey 2013-2015.Pain medicine (Malden, Mass.) · 2019Article
- Midlife reversibility of early-established biobehavioral risk factors: A research agenda.Developmental psychology · 2019Article
- Financial Stress Interacts WithFrontiers in behavioral neuroscience · 2019Article
- Secondary traumatic stress increases expression of proteins implicated in peripheral and central sensitization of trigeminal neurons.Brain research · 2018Article
- Traumatic Experiences, Stressful Events, and Alexithymia in Chronic Migraine With Medication Overuse.Frontiers in psychology · 2018Article
- Opioids Resistance in Chronic Pain Management.Current neuropharmacology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood maltreatment is substantiated in 12 % of children, but nearly 50 % adults recall having been neglected or abused as children. Maltreatment, especially emotional abuse, is associated with migraine. Dysregulation of the HPA axis, autonomic, immune, and metabolic systems appears to be a consequence of maltreatment, and is also reported in migraine. Areas of the brain structurally and functionally affected by childhood abuse and by migraine are also similar, and include the limbic system structures, which connect to pain regions in the brainstem. Putative mechanisms by which early life stress increases the likelihood of developing migraine include gene x environment interactions, in addition to epigenetic modifications via DNA methylation. These modifications are stable and may be transferred across generations, but they may also be reversed by some medications commonly used in migraine, including valproic acid and topiramate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.