ReviewCurrent neurology and neuroscience reports2016
A Review and Update on Tourette Syndrome: Where Is the Field Headed?
Review in Current neurology and neuroscience reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06889480 (MultitArget STereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome), which is not on this map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
MultitArget STereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome
Who cites it
13 citing papers in PubMed, 52 citations in OpenAlex.
- Harnessing the microbiota-gut-brain axis to prevent and treat pediatric neurodevelopmental disorders: translational insights and strategies.Journal of translational medicine · 2025Review
- Identifying potential drug targets for tourette syndrome: a Mendelian randomization study based on druggable genes.Italian journal of pediatrics · 2025Article
- Responsive deep brain stimulation for the treatment of Tourette syndrome.Scientific reports · 2024Article
- Architecture of the subthalamic nucleus.Communications biology · 2024Review
- Review
- Stereotactic Surgery for Treating Intractable Tourette Syndrome: A Single-Center Pilot Study.Brain sciences · 2022Article
- European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part III: pharmacological treatment.European child & adolescent psychiatry · 2022Review
- A Review of Cognitive Outcomes Across Movement Disorder Patients Undergoing Deep Brain Stimulation.Frontiers in neurology · 2019Review
- Tourette Syndrome: A Mini-Review.Frontiers in neurology · 2018Review
- Altered topology of structural brain networks in patients with Gilles de la Tourette syndrome.Scientific reports · 2017Article
- Should we be concerned about preserving agency and personal identity in patients with Adaptive Deep Brain Stimulation systems?AJOB neuroscience · 2017Article
- Deutetrabenazine in Tics Associated with Tourette Syndrome.Tremor and other hyperkinetic movements (New York, N.Y.) · 2016Article
- Tics in the Pediatric Population: Pragmatic Management.Movement disorders clinical practiceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Tourette syndrome (TS) is a childhood onset neurologic disorder with manifestations including multiple motor and phonic tics, and in most cases a variety of behavioral comorbidities such as attention deficit hyperactivity disorder, obsessive compulsive disorder, and other impulse control disorders. Although it is considered a hereditary disorder, likely modified by environmental factors, genetic studies have yet to uncover relevant causative genes and there is no animal model that mimics the broad clinical phenomenology of TS. There has been a marked increase in the number of neurophysiological, neuroimaging, and other studies on TS. The findings from these studies, however, have been difficult to interpret because of small sample sizes, variability of symptoms across patients, and comorbidities. Although anti-dopaminergic drugs are the most widely used medications in the treatment of TS, there has been increasing interest in other drugs, behavioral therapies, and surgical approaches including deep brain stimulation. Herein, we review the current literature and discuss the complexities of TS and the challenges in understanding its pathophysiology and in selecting the most appropriate treatment. We also offer an expert's view of where the field of TS may be headed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.