Observational studyThe Journal of nutrition2016
Dietary Inflammatory Potential during Pregnancy Is Associated with Lower Fetal Growth and Breastfeeding Failure: Results from Project Viva.
Observational study in The Journal of nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 6 of them syntheses that pooled it.
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Who cites it
77 citing papers in PubMed, 6 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- The association between the dietary inflammatory index during pregnancy and risk of gestational diabetes: a prospective cohort study and a meta-analysis.BMC endocrine disorders · 2025Pooled it
- Impact of dietary inflammatory index on gestational diabetes mellitus in normal and overweight women: a systematic review and meta-analysis of observational studies.Asia Pacific journal of clinical nutrition · 2024Pooled it
- Maternal diet in pregnancy and child's respiratory outcomes: an individual participant data meta-analysis of 18 000 children.The European respiratory journal · 2022Pooled it
- Predictors of Adverse Pregnancy Outcomes in Pregnant Women Living with Obesity: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Associations between Maternal Dietary Patterns and Perinatal Outcomes: A Systematic Review and Meta-Analysis of Cohort Studies.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Associations between Dietary Patterns and Inflammatory Markers during Pregnancy: A Systematic Review.Nutrients · 2021Pooled it
- Maternal Dietary Anthocyanidin, Dietary Inflammatory Potential, and Risk of Small-for-Gestational-Age in China.Nutrients · 2025Trial
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- Maternal dietary diversity and dietary quality scores in relation to adverse birth outcomes in Tanzanian women.The American journal of clinical nutrition · 2020Trial
- Impact of lifestyle intervention for obese women during pregnancy on maternal metabolic and inflammatory markers.International journal of obesity (2005) · 2017Trial
- Associations between the Planetary Health Diet in Late Pregnancy and Pregnancy Outcomes in Women with a Raised BMI: Insights from the PEARS Study.Current developments in nutrition · 2026Article
- Maternal Prenatal Diet and Colic and Eczema Among Infants.JAMA network open · 2026Article
- The association of inflammatory potential of diet and height status among adolescent girls: a cross-sectional study in the west of Iran in 2018-2019.BMC women's health · 2026Article
- African American Food Environments and Anti-Inflammatory Intake in Pregnancy.International journal of environmental research and public health · 2026Article
- Relationship between the dietary inflammatory index and immune function during pregnancy - A secondary analysis of the MicrobeMom2 Study.European journal of clinical nutrition · 2026Article
- Recent Choline Intake Is Inversely Associated with Inflammation in Pregnancy - Evidence from the Canadian APrON Cohort.The Journal of nutrition · 2026Article
- Dietary inflammatory index and gestational diabetes mellitus in a multicenter cross sectional study in Suzhou.Frontiers in immunology · 2026Article
- Adherence to the dietary inflammatory index and dietary approaches to stop hypertension and risk of gestational diabetes: a case-control study.BMC pregnancy and childbirth · 2025Article
- Maternal BMI and Diet Quality Modulate Pregnancy Oxidative and Inflammatory Homeostasis.Nutrients · 2025Observational
17 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundInflammation during pregnancy has been linked to adverse maternal and infant outcomes. There is limited information available on the contribution of maternal diet to systemic inflammation and pregnancy health.
objectiveThe objective of this study was to examine associations of maternal prenatal dietary inflammatory index (DII), a composite measure of the inflammatory potential of diet, with markers of maternal systemic inflammation and pregnancy outcomes.
methodsWe studied 1808 mother-child pairs from Project Viva, a pre-birth cohort study in Massachusetts. We calculated the DII from first- and second-trimester food-frequency questionnaires by standardizing the dietary intakes of participants to global means, which were multiplied by the inflammatory effect score and summed. We examined associations of DII with maternal plasma C-reactive protein and white blood cell count in the second trimester and the following perinatal outcomes: gestational diabetes, preeclampsia, length of gestation, fetal growth, mode of delivery, and duration of breastfeeding. We used multivariable linear and logistic regression models to analyze the strength of these associations.
resultsMaternal age was (mean ± SD) 32.2 ± 5.0 y, prepregnancy body mass index (BMI; in kg/m(2)) was 24.9 ± 5.2, and DII was -2.56 ± 1.42 units with a range of -5.4 to 3.7. DII was positively correlated with prepregnancy BMI (Pearson'sr= 0.13,P< 0.0001). Higher DII scores, reflecting more proinflammatory dietary potential, were associated with higher second-trimester plasma CRP (β: 0.08 mg/L per 1-unit increase in maternal DII; 95% CI: 0.02, 0.14) and lower birth weight for gestational agezscore in infants born to obese mothers (β: -0.10zscore per 1-unit increase in maternal DII; 95% CI: -0.18, -0.02). Higher DII scores were associated with lower odds of breastfeeding for at least 1 mo (OR = 0.85; 95% CI: 0.74, 0.98).
conclusionA proinflammatory diet during pregnancy is associated with maternal systemic inflammation and may be associated with impaired fetal growth and breastfeeding failure.
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