ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017
The value of local normal limits in quantitative Thallium-201 CZT MPI SPECT.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Establishment of aAnnals of nuclear medicine · 2025Article
- Automated SPECT analysis compared with expert visual scoring for the detection of FFR-defined coronary artery disease.European journal of nuclear medicine and molecular imaging · 2018Article
- Quantification with normal limits: New cameras and low-dose imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Improving cardiac SPECT accuracy: Old robustness for a new gold standard.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Normal Databases for the Relative Quantification of Myocardial Perfusion.Current cardiovascular imaging reports · 2016Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundConsidering the distinctive characteristics of CZT detectors, automatic quantification of ischemia using normal limits included with software package may deliver suboptimal results for CAD detection. The present study aims to evaluate the benefits of creating normal limits specific to a local population and laboratory protocol. METHODS AND
resultsTwo groups were selected from patients who had undergone a CZT MPI. Normal limits were generated with the QPS application based on the population with low likelihood of CAD. Using the vendor-supplied and the population-specific normal limits i-TPD and vessel-specific SDS results obtained for patients who had subsequently undergone coronary angiography were compared with coronary angiography data. A weak correlation was observed for low i-TPD (stress TPD minus rest TPD) and SDS values. Both databases gave similar values for the area under the ROC curve concerning i-TPD (0.75 to 0.74) and SDS results (0.72 to 0.75 for the LAD, 0.62 to 0.64 for the LCx, and 0.63 to 0.67 for the RCA). Sensitivity (60%), specificity (78%), and predictive positive (84%) and negative (52%) values were also similar with a diagnostic and prognostic threshold value.
conclusionThe use of a population-specific created database did not influence the diagnostic value of thallium-201 MPI QPS results using a CZT camera.
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