ArticleJournal of cardiovascular translational research2016
QUest for the Arrhythmogenic Substrate of Atrial fibRillation in Patients Undergoing Cardiac Surgery (QUASAR Study): Rationale and Design.
Article in Journal of cardiovascular translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Men and women's hearts don't beat the same: Epicardial mapping of Bachmann's bundle.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025Article
- Electrophysiological Markers ofTransplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Unipolar atrial electrogram morphology is affected by age: evidence from high-resolution epicardial mapping.Annals of medicine · 2023Article
- How sex affects the sinus rhythm heartbeat.International journal of cardiology. Heart & vasculature · 2023Article
- Characterization of unipolar electrogram morphology: a novel tool for quantifying conduction inhomogeneity.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Atrial extrasystoles enhance low-voltage fractionation electrograms in patients with atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Does conduction heterogeneity determine the supervulnerable period after atrial fibrillation?Medical & biological engineering & computing · 2023Article
- Epicardial high-resolution mapping of advanced interatrial block: Relating ECG, conduction abnormalities and excitation patterns.Frontiers in cardiovascular medicine · 2022Article
- Optimization of intra-operative electrophysiological localization of the ligament of Marshall.Frontiers in cardiovascular medicine · 2022Article
- AF Inducibility Is Related to Conduction Abnormalities at Bachmann's Bundle.Journal of clinical medicine · 2021Article
- Identification of local atrial conduction heterogeneities using high-density conduction velocity estimation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021Article
- Identification of Low-Voltage Areas: A Unipolar, Bipolar, and Omnipolar Perspective.Circulation. Arrhythmia and electrophysiology · 2021Article
- Conduction Disorders during Sinus Rhythm in Relation to Atrial Fibrillation Persistence.Journal of clinical medicine · 2021Article
- Reduction of Conduction Velocity in Patients with Atrial Fibrillation.Journal of clinical medicine · 2021Article
- Atrial electrophysiological characteristics of aging.Journal of cardiovascular electrophysiology · 2021Article
- Sinus rhythm voltage fingerprinting in patients with mitral valve disease using a high-density epicardial mapping approach.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021Article
- Signal Fingerprinting as a Novel Diagnostic Tool to Identify Conduction Inhomogeneity.Frontiers in physiology · 2021Article
- The Impact of Filter Settings on Morphology of Unipolar Fibrillation Potentials.Journal of cardiovascular translational research · 2020Observational
- Revealing hidden information from unipolar extracellular potentials.HeartRhythm case reports · 2020Article
- Classification of sinus rhythm single potential morphology in patients with mitral valve disease.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2020Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The heterogeneous presentation and progression of atrial fibrillation (AF) implicate the existence of different pathophysiological processes. Individualized diagnosis and therapy of the arrhythmogenic substrate underlying AF may be required to improve treatment outcomes. Therefore, this single-center study aims to identify the arrhythmogenic areas underlying AF by intra-operative, high-resolution, multi-site epicardial mapping in 600 patients with different heart diseases. Participants are divided into 12 groups according to the underlying heart diseases and presence of prior AF episodes. Mapping is performed with a 192-electrode array for 5-10 s during sinus rhythm and (induced) AF of the entire atrial surface. Local activation times are converted into activation and wave maps from which various electrophysiological parameters are derived. Postoperative cardiac rhythm registrations and a 5-year follow-up will show the incidence of postoperative and persistent AF. This project provides the first step in the development of a tool for individual AF diagnosis and treatment.
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