ArticleDigestive diseases and sciences2016
Cannabis Abuse Is Increasing and Associated with Increased Emergency Department Utilization in Gastroenterology Patients.
Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Role of chronic cannabis use: Cyclic vomiting syndrome vs cannabinoid hyperemesis syndrome.Neurogastroenterology and motility · 2019Pooled it
- Cannabis for the treatment of Crohn's disease.The Cochrane database of systematic reviews · 2018Pooled it
- Age Differences in Cannabis Consumption Patterns and in Associations Between Delta-9-Tetrahydrocannabinol Intake and Cannabis Use Disorders Among Adults with Daily Use.Cannabis and cannabinoid research · 2025Article
- Acute care of cyclic vomiting syndrome and cannabinoid hyperemesis syndrome in the home and emergency department.Neurogastroenterology and motility · 2025Review
- The Impact of Cannabis Use on Clinical Outcomes in Inflammatory Bowel Disease: A Population-based Longitudinal Cohort Study.Inflammatory bowel diseases · 2024Article
- Reply: "Cannabis Use: A Marker of Clinical Severity in Inflammatory Bowel Disease?"Inflammatory bowel diseases · 2023Article
- Psychosocial and health problems associated with alcohol use disorder and cannabis use disorder in U.S. adults.Drug and alcohol dependence · 2021Article
- Olfactory Neuroepithelium Cells from Cannabis Users Display Alterations to the Cytoskeleton and to Markers of Adhesion, Proliferation and Apoptosis.Molecular neurobiology · 2021Article
- Cannabis use, other drug use, and risk of subsequent acute care in primary care patients.Drug and alcohol dependence · 2020Article
- U.S. Adults With Pain, a Group Increasingly Vulnerable to Nonmedical Cannabis Use and Cannabis Use Disorder: 2001-2002 and 2012-2013.The American journal of psychiatry · 2020Article
- DSM-5 cannabis withdrawal syndrome: Demographic and clinical correlates in U.S. adults.Drug and alcohol dependence · 2019Article
- Time trends in US cannabis use and cannabis use disorders overall and by sociodemographic subgroups: a narrative review and new findings.The American journal of drug and alcohol abuse · 2019Review
- Is There an Effect of Cannabis Consumption on Acute Pancreatitis?Digestive diseases and sciences · 2018Article
- Emergency Department Burden of Nausea and Vomiting Associated With Cannabis Use Disorder: US Trends From 2006 to 2013.Journal of clinical gastroenterology · 2018Article
- US Epidemiology of Cannabis Use and Associated Problems.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Article
- Predictors of treatment utilization and barriers to treatment utilization among individuals with lifetime cannabis use disorder in the United States.Drug and alcohol dependence · 2017Article
- Cannabis use, attitudes, and legal status in the U.S.: A review.Preventive medicine · 2017Review
- US Adult Illicit Cannabis Use, Cannabis Use Disorder, and Medical Marijuana Laws: 1991-1992 to 2012-2013.JAMA psychiatry · 2017Article
- Therapeutic Use of Cannabis in Inflammatory Bowel Disease.Gastroenterology & hepatology · 2016Article
- Sex Differences in Cannabis Use Disorder Diagnosis Involved Hospitalizations in the United States.Journal of addiction medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe role of cannabinoids in gastrointestinal diseases is controversial and of great interest, yet their use in patients has not been critically examined.
aimTo determine the prevalence and effects of cannabis abuse on healthcare utilization, as measured by emergency department (ED) visits, in a large, tertiary gastroenterology practice.
methodsAll patients seen in the gastroenterology clinic at a tertiary care center during a 27-year period (1986-2013) were included in our study to determine the overall prevalence of cannabis abuse. We matched cannabis abusers 1:2 with non-abusing controls to determine the effect of cannabis on ED utilization, our primary outcome. We used multivariate linear regression to adjust for confounders and define the independent effect of cannabis abuse on ED utilization.
resultsOur prevalence study cohort included 190,303 GI clinic patients with an overall cannabis abuse prevalence of 0.80 % (1520 patients). From 1986 to 2012, the prevalence of cannabis abuse in this clinic increased by 0.73 % (0.03 %/year) (p < 0.0001). From the 1520 cannabis abusers identified, 467 patients were randomly selected as cases and were matched to 934 controls. From this retrospective cohort, the median ED visits/year for cannabis abusers was 1.88 versus 0.89 for non-abusers (p < 0.0001). After multivariate adjustment, cannabis abuse was associated with a 1.47-fold increase (95 % CI 1.23-1.76, p < 0.0001) in median ED visits/year.
conclusionsReported cannabis abuse in GI clinic patients is less prevalent than in the adult US population, but is increasing. Cannabis abuse among gastroenterology patients is associated with increased ED visits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.