ReviewAddiction biology2017
Pathological gambling: a review of the neurobiological evidence relevant for its classification as an addictive disorder.
Review in Addiction biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Shared gray matter alterations in subtypes of addiction: a voxel-wise meta-analysis.Psychopharmacology · 2021Pooled it
- Shared gray matter alterations in individuals with diverse behavioral addictions: A voxel-wise meta-analysis.Journal of behavioral addictions · 2020Pooled it
- Impulsivity in Gambling Disorder and problem gambling: a meta-analysis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Pooled it
- Meta-analyses of clinical neuropsychological tests of executive dysfunction and impulsivity in alcohol use disorder.The American journal of drug and alcohol abuse · 2017Pooled it
- Three Contrasting Accounts of Electronic Gambling Machine Related Harm: Impacts on Community Views Towards Gambling Policy and Responsibility.Journal of gambling studies · 2024Trial
- Effect of transcranial direct current stimulation on decision making and cognitive flexibility in gambling disorder.European archives of psychiatry and clinical neuroscience · 2019Trial
- Trial
- Problematic Online Gaming and Gambling Among First-Year University Students: Identification of Profiles and Psychological Vulnerabilities.Journal of gambling studies · 2026Article
- Association between game addiction and lifetime psychotic-like experiences among high school students: a cross-sectional study.BMC public health · 2025Article
- Striatal cue-reactivity and neurotransmitter function in gambling disorder.Journal of behavioral addictions · 2025Article
- Toward the classification of social media use disorder: Clinical characterization and proposed diagnostic criteria.Addictive behaviors reports · 2025Review
- Computational and Neural Evidence for Altered Fast and Slow Learning from Losses in Problem Gambling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Definition of Substance and Non-substance Addiction.Advances in experimental medicine and biology · 2025Review
- Does the loot box open the door to addiction? A case report of gaming disorder with high charges for loot box purchases.PCN reports : psychiatry and clinical neurosciences · 2024Article
- Decomposition of Reinforcement Learning Deficits in Disordered Gambling via Drift Diffusion Modeling and Functional Magnetic Resonance Imaging.Computational psychiatry (Cambridge, Mass.) · 2024Article
- Internet gaming disorder and tobacco use disorder share neural connectivity patterns between the subcortical and the motor network.Human brain mapping · 2023Article
- Underlying Mechanisms Involved in Gambling Disorder Severity: A Pathway Analysis Considering Genetic, Psychosocial, and Clinical Variables.Nutrients · 2023Article
- Sports wagering in the context of addictive disorders: results from a census-matched U.S. sample.Cogent mental health · 2023Article
- Alcohol and Substance Use Disorders Diagnostic Criteria Changes and Innovations in ICD-11: An Overview.Clinical psychology in Europe · 2022Article
- Neural cue-reactivity in pathological gambling as evidence for behavioral addiction: a systematic review.Current psychology (New Brunswick, N.J.) · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
In light of the upcoming eleventh edition of the International Classification of Diseases (ICD-11), the question arises as to the most appropriate classification of 'Pathological Gambling' ('PG'). Some academic opinion favors leaving PG in the 'Impulse Control Disorder' ('ICD') category, as in ICD-10, whereas others argue that new data especially from the neurobiological area favor allocating it to the category of 'Substance-related and Addictive Disorders' ('SADs'), following the decision in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders. The current review examines important findings in relation to PG, with the aim of enabling a well-informed decision to be made with respect to the classification of PG as a SAD or ICD in ICD-11. Particular attention is given to cognitive deficits and underlying neurobiological mechanisms that play a role in SADs and ICDs. These processes are impulsivity, compulsivity, reward/punishment processing and decision-making. In summary, the strongest arguments for subsuming PG under a larger SAD category relate to the existence of similar diagnostic characteristics; the high co-morbidity rates between the disorders; their common core features including reward-related aspects (positive reinforcement: behaviors are pleasurable at the beginning which is not the case for ICDs); the findings that the same brain structures are involved in PG and SADs, including the ventral striatum. Research on compulsivity suggests a relationship with PG and SAD, particularly in later stages of the disorders. Although research is limited for ICDs, current data do not support continuing to classify PG as an ICD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.