ArticleHippocampus2016
Placing memories in context: Hippocampal representations promote retrieval of appropriate memories.
Article in Hippocampus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Hippocampal communication with the anterior olfactory nucleus is necessary for context-dependent odor memory.Behavioral neuroscience · 2026Article
- Music enhances associative generalization: Evidence from a memory integration task.Memory & cognition · 2026Article
- Distinct neural signatures of hippocampal population dynamics during locomotion-in-place.Scientific reports · 2026Article
- Hippocampal-Prelimbic Coupling During Context-Dependent Extinction Retrieval in Rats.Hippocampus · 2026Article
- Understanding How Acute Alcohol Impacts Neural Encoding in the Rodent Brain.Current topics in behavioral neurosciences · 2025Review
- Effects of social context manipulation on dorsal and ventral hippocampal neuronal responses.Hippocampus · 2023Article
- Emergence of a predictive model in the hippocampus.Neuron · 2023Article
- The limbic memory circuit and the neural basis of contextual memory.Neurobiology of learning and memory · 2022Article
- To learn something new, do something new.Cell research · 2021Article
- Context-dependent odor learning requires the anterior olfactory nucleus.Behavioral neuroscience · 2020Article
- Hippocampal state transitions at the boundaries between trial epochs.Hippocampus · 2020Article
- Analysis of neuronal ensemble activity reveals the pitfalls and shortcomings of rotation dynamics.Scientific reports · 2019Article
- Locus Coeruleus Phasic, But Not Tonic, Activation Initiates Global Remapping in a Familiar Environment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Prefrontal-hippocampal interactions in episodic memory.Nature reviews. Neuroscience · 2017Review
- The influence of low-level stimulus features on the representation of contexts, items, and their mnemonic associations.NeuroImage · 2017Article
- Inhibitory engrams in perception and memory.Proceedings of the National Academy of Sciences of the United States of America · 2017Review
- Navigating Monogamy: Nonapeptide Sensitivity in a Memory Neural Circuit May Shape Social Behavior and Mating Decisions.Frontiers in neuroscience · 2017Review
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Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Returning to a familiar context triggers retrieval of relevant memories, making memories from other contexts less likely to intrude and cause interference. We investigated the physiology that underlies the use of context to prevent interference by recording hippocampal neurons while rats learned two conflicting sets of discrimination problems, either in the same context or in two distinct contexts. Rats that learned the conflicting problem sets in the same context maintained similar neural representations, and performed poorly because conflicting memories interfered with new learning. In contrast, rats that learned in different contexts formed distinct ensemble representations and performed significantly better. We also measured trial-to-trial variation in representations and found that hippocampal activity was directly linked with performance: on trials where an old representation was active, rats were far more likely to make errors. These results show that the formation of distinct hippocampal representations is critical for contextually appropriate memory retrieval. © 2016 Wiley Periodicals, Inc.
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