ArticleNature2016
A hippocampal network for spatial coding during immobility and sleep.
Article in Nature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers.
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Who cites it
124 citing papers in PubMed.
- Article
- High-frequency visual stimulation can increase medial temporal lobe ripple oscillation density.Communications medicine · 2026Article
- Place and behavioral modulation of hippocampal neurons during immobility.Nature communications · 2026Article
- Hippocampal microcircuits constrain the generation of epileptiform activity.bioRxiv : the preprint server for biology · 2026Article
- Distinct goal location beta frequency dynamics in hippocampus and prefrontal cortex across learning.bioRxiv : the preprint server for biology · 2026Article
- A Conserved Mammalian Hippocampal Navigation Motif Reconfigured for Primate Vision.bioRxiv : the preprint server for biology · 2026Article
- Representations of social experience in hippocampal circuits.Trends in cognitive sciences · 2026Review
- GluK1 kainate receptors in parvalbumin interneurons modulate cortico-hippocampal network dynamics during social behavior.Translational psychiatry · 2026Article
- Distinct neural signatures of hippocampal population dynamics during locomotion-in-place.Scientific reports · 2026Article
- A hippocampal 'sharp-wave sleep' state that is dissociable from cortical sleep.Nature neuroscience · 2026Article
- Dynamical modulation of hippocampal replay through firing rate adaptation.Nature communications · 2026Article
- A State-Space Framework for Causal Detection of Hippocampal Ripple-Replay Events.IEEE transactions on bio-medical engineering · 2026Article
- Astrocytic regulation in hippocampal CA2 mediates the impact of sleep deprivation on spatial working memory.Frontiers in systems neuroscience · 2026Article
- Replay without sharp wave ripples in a spatial memory task.Nature communications · 2025Article
- Article
- Disruption of theta-timescale spiking impairs learning but spares hippocampal replay.bioRxiv : the preprint server for biology · 2025Article
- Noncanonical circuits, states, and computations of the hippocampus.Science (New York, N.Y.) · 2025Review
- Integrating endocannabinoid signaling, CCK interneurons, and hippocampal circuit dynamics in behaving animals.Neuron · 2025Review
- Erasable hippocampal neural signatures predict memory discrimination.Cell reports · 2025Article
- Article
64 more citing papers are in PubMed but not listed here.
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6 authors.
Funding
Abstract
How does an animal know where it is when it stops moving? Hippocampal place cells fire at discrete locations as subjects traverse space, thereby providing an explicit neural code for current location during locomotion. In contrast, during awake immobility, the hippocampus is thought to be dominated by neural firing representing past and possible future experience. The question of whether and how the hippocampus constructs a representation of current location in the absence of locomotion has been unresolved. Here we report that a distinct population of hippocampal neurons, located in the CA2 subregion, signals current location during immobility, and does so in association with a previously unidentified hippocampus-wide network pattern. In addition, signalling of location persists into brief periods of desynchronization prevalent in slow-wave sleep. The hippocampus thus generates a distinct representation of current location during immobility, pointing to mnemonic processing specific to experience occurring in the absence of locomotion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.