ArticleMolecular plant pathology2017
Genotyping-by-sequencing-based genome-wide association studies on Verticillium wilt resistance in autotetraploid alfalfa (Medicago sativa L.).
Article in Molecular plant pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 41 citations in OpenAlex.
- Elucidation of genetic architecture for aphid resistance in alfalfa (Medicago sativa) via genome-wide association study.BMC plant biology · 2025Article
- Phenotypic and genomic insights into alfalfa diversity: Identifying critical loci for enhanced resilience.The plant genome · 2025Article
- Genome-wide association study identifies quantitative trait loci associated with resistance to Verticillium dahliae race 3 in tomato.The plant genome · 2025Article
- Unraveling key genes and pathways involved in Verticillium wilt resistance by integrative GWAS and transcriptomic approaches in Upland cotton.Functional & integrative genomics · 2025Article
- Genome-wide association study revealed candidate genes associated with leaf size in alfalfa (Medicago sativa L.).BMC plant biology · 2025Article
- Unveiling alfalfa root rot resistance genes through an integrative GWAS and transcriptome study.BMC plant biology · 2025Article
- Genome-wide association studies reveal potential candidate genes associated with amino acid in tea plants.PeerJ · 2025Article
- Discovering new genes for alfalfa (Frontiers in plant science · 2024Article
- Analysis of genetic diversity and genome-wide association study for drought tolerance related traits in Iranian bread wheat.BMC plant biology · 2023Article
- Application of machine learning to explore the genomic prediction accuracy of fall dormancy in autotetraploid alfalfa.Horticulture research · 2023Article
- Article
- Genome-wide association mapping for wheat morphometric seed traits in Iranian landraces and cultivars under rain-fed and well-watered conditions.Scientific reports · 2022Article
- Research Progress and Prospect of Alfalfa Resistance to Pathogens and Pests.Plants (Basel, Switzerland) · 2022Review
- Two linked resistance genes function divergently in defence against Verticillium Wilt in Alfalfa.Plant biotechnology journal · 2022Article
- Genome Assembly of Alfalfa Cultivar Zhongmu-4 and Identification of SNPs Associated with Agronomic Traits.Genomics, proteomics & bioinformatics · 2022Article
- Genome-wide association study of six quality-related traits in common wheat (Triticum aestivum L.) under two sowing conditions.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Agro-Morphological, Yield, and Genotyping-by-Sequencing Data of Selected Wheat (Frontiers in genetics · 2021Article
- Biotechnological Perspectives of Omics and Genetic Engineering Methods in Alfalfa.Frontiers in plant science · 2020Review
- High-density linkage map construction and mapping QTL for yield and yield components in autotetraploid alfalfa using RAD-seq.BMC plant biology · 2019Article
- Tools for Genetic Studies in Experimental Populations of Polyploids.Frontiers in plant science · 2018Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Verticillium wilt (VW) is a fungal disease that causes severe yield losses in alfalfa. The most effective method to control the disease is through the development and use of resistant varieties. The identification of marker loci linked to VW resistance can facilitate breeding for disease-resistant alfalfa. In the present investigation, we applied an integrated framework of genome-wide association with genotyping-by-sequencing (GBS) to identify VW resistance loci in a panel of elite alfalfa breeding lines. Phenotyping was performed by manual inoculation of the pathogen to healthy seedlings, and scoring for disease resistance was carried out according to the standard test of the North America Alfalfa Improvement Conference (NAAIC). Marker-trait association by linkage disequilibrium identified 10 single nucleotide polymorphism (SNP) markers significantly associated with VW resistance. Alignment of the SNP marker sequences to the M. truncatula genome revealed multiple quantitative trait loci (QTLs). Three, two, one and five markers were located on chromosomes 5, 6, 7 and 8, respectively. Resistance loci found on chromosomes 7 and 8 in the present study co-localized with the QTLs reported previously. A pairwise alignment (blastn) using the flanking sequences of the resistance loci against the M. truncatula genome identified potential candidate genes with putative disease resistance function. With further investigation, these markers may be implemented into breeding programmes using marker-assisted selection, ultimately leading to improved VW resistance in alfalfa.
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