Evidence map›Paper›PMID 26933739›Full record

ReviewCell chemical biology2016

Glycan Engineering for Cell and Developmental Biology.

Matthew E Griffin, Linda C Hsieh-Wilson

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell chemical biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 84 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Introduction of Carbonyl Groups into Antibodies.Molecules (Basel, Switzerland) · 2023
    Review
  6. Cell Surface Engineering Tools for Programming Living Assemblies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Chemical reporters to study mammalian O-glycosylation.Biochemical Society transactions · 2021
    Review
  16. Recent Advances in the Chemical Biology ofMolecules (Basel, Switzerland) · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew E GriffinDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Linda C Hsieh-WilsonDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: lhw@caltech.edu.
California Institute of Technology · US

Funding

Role of Fucosyl Saccharides and O-GlcNAc Glycosylation in Neuronal CommunicationR01GM084724 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HSIEH-WILSON, LINDA C · 2007 to 2016
$3.6M
A chemical approach to elucidating the structure-function relationships of chondronitin sulfate glycosaminoglycansR01GM093627 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HSIEH-WILSON, LINDA C · 2010 to 2018
$3.6M
NIGMS NIH HHS R01 GM084724NIGMS NIH HHS R01-GM084724NIGMS NIH HHS R01 GM093627NIGMS NIH HHS R01-GM093627
6 · The paper itself

Abstract

Cell-surface glycans are a diverse class of macromolecules that participate in many key biological processes, including cell-cell communication, development, and disease progression. Thus, the ability to modulate the structures of glycans on cell surfaces provides a powerful means not only to understand fundamental processes but also to direct activity and elicit desired cellular responses. Here, we describe methods to sculpt glycans on cell surfaces and highlight recent successes in which artificially engineered glycans have been employed to control biological outcomes such as the immune response and stem cell fate.

Indexed as

AnimalsBiosynthetic PathwaysCytological TechniquesDevelopmental BiologyGenetic EngineeringHumansImmunityOligosaccharidesPolysaccharidesStem CellsOligosaccharidesPolysaccharides

Identifiers

PMID26933739
PMCPMC4857608
OpenAlexW2250233848

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.