Evidence map›Paper›PMID 26933261›Full record

Trial reportThe Canadian veterinary journal = La revue veterinaire canadienne2016

Behavioral response and cost comparison of manual versus pharmacologic restraint protocols in healthy dogs.

Michele Barletta, Marc Raffe

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in The Canadian veterinary journal = La revue veterinaire canadienne, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michele BarlettaCollege of Veterinary Medicine, Department of Large Animal Medicine, 501 DW Brooks Drive, University of Georgia, Athens, Georgia 30602, USA (Barletta); Outcomes Research, Zoetis Inc, 100 Campus Drive, Florham Park, New Jersey 07932, USA (Raffe).
Marc RaffeCollege of Veterinary Medicine, Department of Large Animal Medicine, 501 DW Brooks Drive, University of Georgia, Athens, Georgia 30602, USA (Barletta); Outcomes Research, Zoetis Inc, 100 Campus Drive, Florham Park, New Jersey 07932, USA (Raffe).
University of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although sedatives are routinely administered to dogs for diagnostic and minimally invasive procedures, manual restraint is often used. The study compared intra-procedural behavioral response, scored on a 100-point, visual analog scale, and cost of restraint in healthy dogs given 1 of 5 treatments: manual restraint, dexmedetomidine at 125 μg/m(2) (Dex 125) or 375 μg/m(2) (Dex 375), Dex 125 plus butorphanol at 0.4 mg/kg (Dex 125 + Bu), or Dex 375 plus butorphanol at 0.4 mg/kg (Dex 375 + Bu). Mean behavioral response scores in dogs declined from baseline in the manual restraint group and improved in a linear fashion in the group order Dex 125, Dex 375, Dex 125 + Bu, and Dex 375 + Bu. Dexmedetomidine at 375 μg/m(2) or at 125 μg/m(2) or at 375 μg/m(2) in combination with butorphanol produced the best intra-procedural behavioral response. The cost of sedative drugs was offset by the opportunity cost of diverting personnel from revenue-generating activity to manual restraint.

Indexed as

DogsAdrenergic alpha-2 Receptor AgonistsAnalgesics, OpioidAnimalsBehavior, AnimalButorphanolDexmedetomidineDrug Therapy, CombinationFemaleHypnotics and SedativesMaleProcedural SedationRestraint, PhysicalAdrenergic alpha-2 Receptor AgonistsAnalgesics, OpioidButorphanolDexmedetomidineHypnotics and Sedatives

Identifiers

PMID26933261
PMCPMC4751764
OpenAlexW2471886759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.