Evidence map›Paper›PMID 26933222›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2016

Alzheimer's disease CD33 rs3865444 variant does not contribute to cognitive performance.

Guiyou Liu, Qinghua Jiang

Abstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The Neurotherapeutic Arsenal inMolecules (Basel, Switzerland) · 2024
    Review
  3. The relationship of early- and late-onset Alzheimer's disease genes with COVID-19.Journal of neural transmission (Vienna, Austria : 1996) · 2022
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Innate immune activation in Alzheimer's disease.Annals of translational medicine · 2018
    Review
  14. Article
  15. Article
  16. Article
  17. Rs4878104 contributes to Alzheimer's disease risk and regulates DAPK1 gene expression.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017
    Article
  18. Article
  19. Article
  20. Reply to Liu and Jiang: Maintenance of postreproductive cognitive capacity by inclusive fitness.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Guiyou LiuCenter for Bioinformatics, School of Life Science and Technology, Harbin Institute of Technology, Harbin 150080, China.
Qinghua JiangCenter for Bioinformatics, School of Life Science and Technology, Harbin Institute of Technology, Harbin 150080, China qhjiang@hit.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic FitnessAlzheimer DiseaseAnimalsBrainCognition DisordersHumansSialic Acid Binding Ig-like Lectin 3Sialic Acid Binding Ig-like Lectin 3

Identifiers

PMID26933222
PMCPMC4812757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.