ArticleClinical journal of the American Society of Nephrology : CJASN2016
Height at First RRT and Mortality in Children.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Nutritional profile and infection-related hospital admissions in children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2025Article
- Indoxyl Sulfate Contributes to Impaired Height Velocity in (Pre)School Children.Kidney international reports · 2024Article
- Role of Nutrients in Pediatric Non-Dialysis Chronic Kidney Disease: From Pathogenesis to Correct Supplementation.Biomedicines · 2024Review
- Anthropometric measures and patient outcome in pediatric chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2023Article
- Associations of longitudinal height and weight with clinical outcomes in pediatric kidney replacement therapy: results from the ESPN/ERA Registry.Pediatric nephrology (Berlin, Germany) · 2023Article
- Longitudinal Relationship Between Anemia and Statural Growth Impairment in Children and Adolescents With Nonglomerular CKD: Findings From the Chronic Kidney Disease in Children (CKiD) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023Article
- Malnutrition Patterns in Children with Chronic Kidney Disease.Life (Basel, Switzerland) · 2023Review
- Epidemiology of pediatric chronic kidney disease/kidney failure: learning from registries and cohort studies.Pediatric nephrology (Berlin, Germany) · 2022Review
- Determinants of growth after kidney transplantation in prepubertal children.Pediatric nephrology (Berlin, Germany) · 2021Article
- Targeting optimal PD management in children: what have we learned from the IPPN registry?Pediatric nephrology (Berlin, Germany) · 2021Review
- Strategies for Optimizing Growth in Children With Chronic Kidney Disease.Frontiers in pediatrics · 2020Review
- Serum albumin and hospitalization among pediatric patients with end-stage renal disease who started dialysis therapy.Pediatric nephrology (Berlin, Germany) · 2019Article
- Short stature in advanced pediatric CKD is associated with faster time to reduced kidney function after transplant.Pediatric nephrology (Berlin, Germany) · 2019Article
- Determinants of Statural Growth in European Children With Chronic Kidney Disease: Findings From the Cardiovascular Comorbidity in Children With Chronic Kidney Disease (4C) Study.Frontiers in pediatrics · 2019Article
- Associations Between Weight Loss, Kidney Function Decline, and Risk of ESRD in the Chronic Kidney Disease in Children (CKiD) Cohort Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018Observational
- Survival in children requiring chronic renal replacement therapy.Pediatric nephrology (Berlin, Germany) · 2018Review
- Clinical outcomes and survival in pediatric patients initiating chronic dialysis: a report of the NAPRTCS registry.Pediatric nephrology (Berlin, Germany) · 2017Article
- Lack of hepcidin ameliorates anemia and improves growth in an adenine-induced mouse model of chronic kidney disease.American journal of physiology. Renal physiology · 2016Article
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Authors and funding
7 authors.
Funding
Abstract
BACKGROUND AND
objectivesPoor linear growth is common in children with CKD and has been associated with higher mortality. However, recent data in adult dialysis patients have suggested a higher risk of death in persons of tall stature. In this study, we aimed to examine the risk of all-cause and cause-specific mortality in children at both extremes of height at the time of first RRT. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Using the US Renal Data System, we performed a retrospective analysis of 13,218 children aged 2-19 years, who received their first RRT (dialysis or transplant) during 1995-2011. We used adjusted Cox models to examine the association between short (<3rd percentile) and tall (>3rd percentile) stature and risk of death, compared with less extreme heights.
resultsOver a median follow-up of 7.1 years, there were 1721 deaths. Risk of death was higher in children with short (hazard ratio, 1.49; 95% confidence interval, 1.33 to 1.66) and tall stature (hazard ratio, 1.32; 95% confidence interval, 1.03 to 1.69) in adjusted analysis. In secondary analyses, there was a statistically significant interaction between height and body mass index categories (P=0.04), such that the association of tall stature with higher mortality was limited to children with elevated body mass index (defined as ≥95th percentile for age and sex). Children with short stature had a higher risk of cardiac- and infection-related death, whereas children with tall stature had a higher risk of cancer-related death.
conclusionsChildren with short and tall stature are at higher mortality risk, although this association was modified by body mass index at time of first RRT. Studies to further explore the reasons behind the higher risk of mortality in children with extremes of height at the time of first RRT are warranted.
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