Evidence map›Paper›PMID 26932503›Full record

ReviewEuropean journal of nutrition2016

Caffeine and cardiovascular diseases: critical review of current research.

Anthony Zulli, Renee M Smith, Peter Kubatka, Jan Novak, Yoshio Uehara, Hayley Loftus, Tawar Qaradakhi, Miroslav Pohanka, Nazarii Kobyliak, Angela Zagatina and 5 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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  17. NMR, RP-HPLC-PDA-ESI-MSMolecules (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Anthony ZulliCentre for Chronic Disease (CCD), College of Health and Biomedicine, Victoria University, Melbourne, VIC, Australia.
Renee M SmithCentre for Chronic Disease (CCD), College of Health and Biomedicine, Victoria University, Melbourne, VIC, Australia.
Peter KubatkaDepartment of Medical Biology, Jessenius Faculty of Medicine, Comenius University in Bratislava, Martin, Slovakia.
Jan Novak2nd Department of Internal Medicine, St. Anne's University Hospital and Masaryk University, Brno, Czech Republic.
Yoshio UeharaDivision of Clinical Nutrition, Faculty of Home Economics, Kyoritsu Women's University, Tokyo, Japan.
Hayley LoftusCentre for Chronic Disease (CCD), College of Health and Biomedicine, Victoria University, Melbourne, VIC, Australia.
Tawar QaradakhiCentre for Chronic Disease (CCD), College of Health and Biomedicine, Victoria University, Melbourne, VIC, Australia.
Miroslav PohankaFaculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic.
Nazarii KobyliakBogomolets National Medical University, Kiev, Ukraine.
Angela ZagatinaCardiology Center Medika, St. Petersburg, Russia.
Jan KlimasDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University, Odborarov 10, 832 32, Bratislava, Slovak Republic.
Alan HayesCentre for Chronic Disease (CCD), College of Health and Biomedicine, Victoria University, Melbourne, VIC, Australia.
Giampiero La RoccaHuman Anatomy Section, Department of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Palermo, Italy.
Miroslav Soucek2nd Department of Internal Medicine, St. Anne's University Hospital and Masaryk University, Brno, Czech Republic.
Peter KruzliakLaboratory of Structural Biology and Proteomics, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Palackeho tr 1/1946, Brno, 612 42, Czech Republic. kruzliakpeter@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements. This wide use has led to concerns regarding the safety of caffeine and its proposed beneficial role in alertness, performance and energy expenditure and side effects in the cardiovascular system. The question remains "Which dose is safe?", as the population does not appear to adhere to the strict guidelines listed on caffeine consumption. Studies in humans and animal models yield controversial results, which can be explained by population, type and dose of caffeine and low statistical power. This review will focus on comprehensive and critical review of the current literature and provide an avenue for further study.

Indexed as

AnimalsBlood VesselsCaffeineCardiovascular DiseasesClinical Studies as TopicCoffeeDisease Models, AnimalDose-Response Relationship, DrugHeartHumansMeta-Analysis as TopicMetabolic SyndromeCaffeineCoffeeCaffeineCardioprotective effectsCardiovascular diseasesClinical studiesExperimental studiesPathogenesis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.