ArticlePlant physiology2016
Chloroplasts Are Central Players in Sugar-Induced Leaf Growth.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 61 citations in OpenAlex.
- Ustilago maydis disrupts carbohydrate signaling networks to induce hypertrophy in host cells.Nature communications · 2026Article
- Regulation of Rubisco activity by interaction with chloroplast metabolites.The Biochemical journal · 2024Article
- Genome-wide identification of GA2ox genes family and analysis of PbrGA2ox1-mediated enhanced chlorophyll accumulation by promoting chloroplast development in pear.BMC plant biology · 2024Article
- Leaf photosynthetic characteristics of waxy maize in response to different degrees of heat stress during grain filling.BMC plant biology · 2023Article
- Correlated retrograde and developmental regulons implicate multiple retrograde signals as coordinators of chloroplast development in maize.The Plant cell · 2022Article
- Glucose-6-P/phosphate translocator2 mediates the phosphoglucose-isomerase1-independent response to microbial volatiles.Plant physiology · 2022Article
- Cotton (International journal of molecular sciences · 2022Article
- Comparative transcriptome analysis provides insight into the molecular mechanisms of long-day photoperiod inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- PRAT Proteins Operate in Organellar Protein Import and Export inPlants (Basel, Switzerland) · 2021Article
- Integrated transcript and metabolite profiling reveals coordination between biomass size and nitrogen metabolism inPlant biotechnology (Tokyo, Japan) · 2021Article
- Distinctive mitochondrial and chloroplast components contributing to the maintenance of carbon balance during plant growth at elevated COPlant signaling & behavior · 2020Article
- Photoperiod and temperature as dominant environmental drivers triggering secondary growth resumption in Northern Hemisphere conifers.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Morpho-physiological integrators, transcriptome and coexpression network analyses signify the novel molecular signatures associated with axillary bud in chrysanthemum.BMC plant biology · 2020Article
- Spatial Nano-Morphology of the Prolamellar Body in EtiolatedFrontiers in cell and developmental biology · 2020Article
- Association analysis of phenotypic and metabolomic changes in Arabidopsis accessions and their FPlant biotechnology (Tokyo, Japan) · 2019Article
- WRKY18 and WRKY53 Coordinate with HISTONE ACETYLTRANSFERASE1 to Regulate Rapid Responses to Sugar.Plant physiology · 2019Article
- Highly Resolved Systems Biology to Dissect the Etioplast-to-Chloroplast Transition in Tobacco Leaves.Plant physiology · 2019Article
- Transcriptome and metabolome reveal distinct carbon allocation patterns during internode sugar accumulation in different sorghum genotypes.Plant biotechnology journal · 2019Article
- Organelle DNA contents and starch accumulation in potato tubers.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- The role of HEXOKINASE1 in Arabidopsis leaf growth.Plant molecular biology · 2019Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leaves are the plant's powerhouses, providing energy for all organs through sugar production during photosynthesis. However, sugars serve not only as a metabolic energy source for sink tissues but also as signaling molecules, affecting gene expression through conserved signaling pathways to regulate plant growth and development. Here, we describe an in vitro experimental assay, allowing one to alter the sucrose (Suc) availability during early Arabidopsis (Arabidopsis thaliana) leaf development, with the aim to identify the affected cellular and molecular processes. The transfer of seedlings to Suc-containing medium showed a profound effect on leaf growth by stimulating cell proliferation and postponing the transition to cell expansion. Furthermore, rapidly after transfer to Suc, mesophyll cells contained fewer and smaller plastids, which are irregular in shape and contain fewer starch granules compared with control mesophyll cells. Short-term transcriptional responses after transfer to Suc revealed the repression of well-known sugar-responsive genes and multiple genes encoded by the plastid, on the one hand, and up-regulation of a GLUCOSE-6-PHOSPHATE TRANSPORTER (GPT2), on the other hand. Mutant gpt2 seedlings showed no stimulation of cell proliferation and no repression of chloroplast-encoded transcripts when transferred to Suc, suggesting that GPT2 plays a critical role in the Suc-mediated effects on early leaf growth. Our findings, therefore, suggest that induction of GPT2 expression by Suc increases the import of glucose-6-phosphate into the plastids that would repress chloroplast-encoded transcripts, restricting chloroplast differentiation. Retrograde signaling from the plastids would then delay the transition to cell expansion and stimulate cell proliferation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.