ArticleDeutsches Arzteblatt international2016
The Prevalence of Renal Failure. Results from the German Health Interview and Examination Survey for Adults, 2008-2011 (DEGS1).
Article in Deutsches Arzteblatt international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- The Management of Chronic Kidney Disease not Requiring Renal Replacement Therapy in General Practice.Deutsches Arzteblatt international · 2025Guideline
- Global health inequalities of chronic kidney disease: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Pooled it
- The Effects of Intensive Versus Routine Treatment in Patients with Acute Kidney Injury.Deutsches Arzteblatt international · 2020Trial
- Early integration of palliative care in outpatient nephrology: exploring healthcare professionals' knowledge, attitudes, and communication practices - an exploratory multi-methods study.BMC nephrology · 2026Article
- Glomerular Filtration Rate, Albuminuria, and Reported Kidney Disease in Comparison: Results From the German National Cohort (NAKO).Deutsches Arzteblatt international · 2026Observational
- Dietary phosphate exposure-strategies to protect vulnerable population groups.Archives of toxicology · 2026Review
- Prevalence of Obesity, Comorbidities, and Eligibility for Pre-Transplant Bariatric Surgery in 275 Patients Awaiting Kidney Transplant at a Single Center in Germany.Annals of transplantation · 2026Article
- Sex and Gender Differences in Chronic Kidney Disease-Explained by the Brenner-Luyckx Concept of Hyperfiltration.Journal of clinical medicine · 2026Review
- Increased albuminuria is highly prevalent in the general population: prevalence of CKD in the Gutenberg Health Study.Clinical kidney journal · 2026Article
- The Synergistic Treatment of Heart and Kidney Disease.Deutsches Arzteblatt international · 2026Review
- [InspeCKD: an analysis of the prevalence, diagnosis, and treatment of chronic kidney disease : Data from at-risk patients in German primary care].Innere Medizin (Heidelberg, Germany) · 2025Article
- Prevalence and characteristics of chronic kidney disease in the Hamburg City Health Study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Article
- Multicenter Renal Pharmacist Group-Pharmaceutical Care for Patients with Renal Impairment at Four Non-University Hospitals in Germany.Journal of clinical medicine · 2025Article
- Insomnia and sleep duration for kidney function: Mendelian randomization study.Renal failure · 2024Article
- Onconephrology: The Significance of Renal Function for the Development, Diagnosis, and Treatment of Cancer.Deutsches Arzteblatt international · 2024Review
- Monogenic Kidney Diseases in Adults With Chronic Kidney Disease (CKD).Deutsches Arzteblatt international · 2024Review
- The Early Diagnosis and Treatment of Chronic Renal Insufficiency.Deutsches Arzteblatt international · 2024Review
- Imaging Markers Derived From MRI-Based Automated Kidney Segmentation—an Analysis of Data From the German National Cohort (NAKO Gesundheitsstudie).Deutsches Arzteblatt international · 2024Observational
- Age- and Sex-Specific Reference Values for Renal Volume and Association with Risk Factors for Chronic Kidney Disease in a General Population-An MRI-Based Study.Journal of clinical medicine · 2024Article
- Prevalence of undetected chronic kidney disease in high-risk middle-aged patients in primary care: a cross-sectional study.Frontiers in medicine · 2024Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of non-end stage renal failure among adults in Germany is unknown. Accurate figures would enable us to estimate the overall need for kidney replacement therapies and the unexploited potential for disease prevention. Renal failure is also an important cardiovascular risk factor. Until now, American prevalence figures have often been applied to Germany despite dissimilarities between the two populations.
methodsWe analyzed data on renal function from the nationwide German Health Interview and Examination Survey for Adults, 2008-2011 (DEGS1), which was carried out by the Robert Koch Institute. The glomerular filtration rate was estimated (eGFR) from the serum creatinine and cystatin C levels (CKD-EPI formula) and a semiquantitative measure of albuminuria. Relationships between renal failure and its possible determinants were quantified with adjusted prevalence ratios (PR) and 95% confidence intervals (95% CI).
resultsRoughly 2.3% (95% CI: [1.9; 2.6 ]) of persons aged 18-79 had an eGFR below 60 mL/min/1.73 m2. The prevalence rose with age. We extrapolated these figures conservatively to persons aged 80 and above, who were not included in the DEGS1, and arrived at a figure of at least 2 million persons in Germany with renal failure. 11.5% of the population have albuminuria of at least 30 mg/L. Diabetes mellitus (PR = 2.25, 95% CI: [1.59; 3.16]) and arterial hypertension (PR = 3.46, 95% CI: [1.95; 6.12]) are important determinants.
conclusionThis study provides the first representative estimate of the prevalence of renal failure in Germany. The condition is highly dependent on age but less prevalent than previously assumed on the basis of American prevalence figures.
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