Evidence map›Paper›PMID 26931445›Full record

ArticleThe Journal of infectious diseases2016

Human Papillomavirus (HPV) L1 Serum Antibodies and the Risk of Subsequent Oral HPV Acquisition in Men: The HIM Study.

Christine M Pierce Campbell, Raphael P Viscidi, B Nelson Torres, Hui-Yi Lin, William Fulp, Martha Abrahamsen, Eduardo Lazcano-Ponce, Luisa L Villa, Aimée R Kreimer, Anna R Giuliano

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 127 citations in OpenAlex.

  1. Observational
  2. Review
  3. Factors Associated With Persistence and Clearance of High-Risk Oral Human Papillomavirus (HPV) Among Participants in the HPV Infection in Men (HIM) Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  4. Article
  5. Article
  6. Review
  7. An Examination of HPV16 Natural Immunity in Men Who Have Sex with Men (MSM) in the HPV in Men (HIM) Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Christine M Pierce CampbellDepartment of Cancer Epidemiology.
Raphael P ViscidiDepartment of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore.
B Nelson TorresDepartment of Cancer Epidemiology.
Hui-Yi LinDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center and Research Institute, Tampa, Florida.
William FulpDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center and Research Institute, Tampa, Florida.
Martha AbrahamsenDepartment of Cancer Epidemiology.
Eduardo Lazcano-PonceCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, México.
Luisa L VillaDepartment of Radiology and Oncology, School of Medicine, University of São Paulo Cancer Institute of the State of São Paulo, Brazil.
Aimée R KreimerDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Anna R GiulianoDepartment of Cancer Epidemiology.
Moffitt Cancer Center · USInstituto do Câncer do Estado de São Paulo · BRInstituto Nacional de Salud Pública · MXJohns Hopkins Medicine · USNational Institutes of Health · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI KENNETH Lynn WRIGHT · 1998 to 2026
$93.5M
Natural History of HPV Infection in Men: The HIM StudyR01CA098803 · NCI · H. LEE MOFFITT CANCER CTR &RES INST · PI GIULIANO, ANNA R. · 2004 to 2014
$18.2M
NCI NIH HHS P30 CA076292NCI NIH HHS R01 CA098803
6 · The paper itself

Abstract

The role of antibody-mediated immunity in preventing newly acquired oral human papillomavirus (HPV) is not well understood. Among 1618 men participating in the HPV Infection in Men (HIM) Study, we evaluated oral rinses for HPV DNA and baseline sera for HPV-6, -11, -16, and -18 L1 antibodies. Thirty percent of men (486) were seropositive for ≥1 HPV type, and 25 men developed incident oral HPV infection (HPV-6 was detected in 7, HPV-11 in 0, HPV-16 in 17, and HPV-18 in 1). Cox models revealed that men with circulating antibodies to HPV-6, -11, -16, or -18 were not less likely to acquire type-specific oral HPV than men without antibodies (hazard ratio for the risk of acquiring HPV-6, -11, -16, or -18, 1.63; 95% confidence interval, .56-4.76).

Indexed as

AdolescentAdultAgedAntibodies, ViralBrazilHumansMaleMexicoMiddle AgedOropharyngeal NeoplasmsPapillomaviridaePapillomavirus InfectionsProportional Hazards ModelsProspective StudiesRisk AssessmentUnited StatesAntibodies, ViralantibodiesHPV16menoral HPVserology

Identifiers

PMID26931445
PMCPMC4907411
OpenAlexW2318524296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.